PMID: 9244099Jul 1, 1997

Blockage of mesenteric lymphatic flow in rats

Pediatric Surgery International
H TsuchiyaT Nemoto

Abstract

An experimental model of blockage of the mesenteric lymphatic flow (MLF) in rats was designed, and morphologic changes of mesenteric lymphatic vessels (MLV) and lymph nodes were investigated by mesenteric lymphangiography and histopathologic examination. Body weight in rats with blockage of MLF did not increase normally. Mesenteric lymphangiography revealed dilation of the MLV, reverse flow into the peripheral MLV, and leakage of contrast medium, resulting in chylous ascites. Remarkable dilation of the lymphatic sinuses and dilated and increased rough endoplasmic reticulum in lymphocytes in the mesenteric lymph nodes due to lymph stagnation were observed by light and electron microscopic examination, respectively.

Related Concepts

Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Extravasation
Lymphography
Weighing Patient
Mesentery
Pathological Dilatation
Chylous Peritonitis
Lymph
Lymph Nodes
Microscopy

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