PMID: 2863043Jan 1, 1985

Blood acid-base status, whole blood and whole body buffer values in sand rats (Psammomys obesus) exposed to hypercapnia

Comparative Biochemistry and Physiology. A, Comparative Physiology
A Bar-IlanS Samueloff


Arterial blood acid-base status of unanesthetized sand rats (Psammomys obesus) were studied under normocapnic and hypercapnic conditions, and compared to those obtained for the albino rat (Rattus norvegicus). The average control blood pH: 7.396 +/- 0.034; PaCO2: 30.5 +/- 2.9 mmHg; HCO-3: 18.8 +/- 2.5 mM/l; and HCO-3 std: 20.9 +/- 2.1 (N = 15) obtained here for the sand rat are in the lower range of values found in other mammals and indicate a status of partially compensated metabolic acidosis. The blood buffer values of the sand rat, delta log PCO2/delta pH = -2.32 +/- 0.35 (N = 25) are significantly higher than those found here for the rat, delta log PCO2/delta pH = -1.51 +/- 0.10 (N = 39), and those reported for other mammals. This high blood buffer value may be related to the natural high mineral diet of the sand rat. The in vivo (whole body) buffer value delta log PaCO2/delta pH = -1.41 and -1.65 for the sand rat and the rat found here are higher than those reported for the man and dog and may represent a physiological adaptation to the hypercapnic conditions prevailing in underground burrows.


Oct 11, 1992·Respiration Physiology·B R Williams, D L Kilgore
Apr 1, 1993·Journal of Basic and Clinical Physiology and Pharmacology·B Pinshow


Mar 7, 1978·Journal of Theoretical Biology·K J Wilson, D L Kilgore
Mar 1, 1972·Life Sciences. Pt. 1: Physiology and Pharmacology·G Frenkel, P F Kraicer
Jul 1, 1973·European Journal of Clinical Investigation·P LeuenbergerD R Held
Jan 1, 1968·Respiration Physiology·J C MithoeferW F Porter
Jan 1, 1984·Comparative Biochemistry and Physiology. A, Comparative Physiology·A Bar-IlanS Samueloff
Mar 1, 1980·Pflügers Archiv : European journal of physiology·A Bar-Ilan, J Marder
Apr 1, 1982·Respiration Physiology·M Brun-PascaudJ J Pocidalo
May 1, 1964·The Journal of Clinical Investigation·J J COHENW B SCHWARTZ

Related Concepts

Whole Blood
August Rats
Rats, Sand
Whole Body
Compensated Metabolic Acidosis
Gases, Blood, pH Only
Psammomys obesus

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Comparative Biochemistry and Physiology. A, Comparative Physiology
A Bar-IlanS Samueloff
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
D F Boggs, G F Birchard
© 2020 Meta ULC. All rights reserved