Blood and marrow transplantation in the People's Republic of China

Bone Marrow Transplantation
T Wu, D-P Lu

Abstract

Syngeneic BMT was first performed successfully in China in 1964. In 1981, allogeneic BMT was applied in an acute leukemia patient with success. Since then, the number of BMTs has been increasing gradually, especially since the 1990s. More than 2000 stem cell transplants per year have been performed in recent years in more than 50 BMT units in mainland China. A survey of 16 BMT units from 1986 to 2005 indicates that the predominant types of transplantation performed are identical sibling (36%), related mismatched/haploidentical (11.2%), unrelated (7.5%) and autologous (44.5%) and that the distribution of disease entities and prevalent diseases being transplanted are AML (31%), ALL (16.1%), CML (19.1%) and lymphoid malignancy (22.2%). The number of transplants from unrelated donor or related mismatched/haploidentical donor has increased significantly in the past 5 years. BM and G-CSF-mobilized peripheral blood are used about equally often as a source of hematopoietic stem cells, or they are used in combination. Umbilical cord blood is used least often. Leukemias for allogeneic and lymphoid malignancies for autologous BMT continue to increase, but the increase in BMT for CML has been slow since 2004. By the end of 2007, HLA data w...Continue Reading

Citations

Mar 2, 2010·Bone Marrow Transplantation·A YoshimiUNKNOWN Asia-Pacific Blood and Marrow Transplantation Group (APBMT)
Nov 17, 2009·BMC Complementary and Alternative Medicine·Jianling JinPeiji Gao
Aug 15, 2009·Current Opinion in Hematology·Alois Gratwohl, Helen Baldomero

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