Blood component therapy.

Indian Journal of Pediatrics
Anupam Verma, Hemlata

Abstract

The blood component support in pediatric patients is more challenging as compared to adult patients, as such, a thorough understanding of various blood components and indications for each is critical when making the decision for transfusion. Transfusion needs in pediatric group parallel the changes that accompany the transitions from fetus to neonate, neonate to infant, and throughout childhood. Modified or unmodified blood components viz. red blood cells, platelets, granulocytes, fresh frozen plasma and cryoprecipitate are required for transfusion support in pediatric population. In general, fetuses and infants younger than 4 months of age have specialized transfusion requirements whereas transfusion of infants older than 4 months and children parallels those for adults. Transfusion practices differ widely among pediatric care units depending upon individual preferences, hospital transfusion policy and resource availability. There is a need to implement best transfusion practices and despite the lack of firm evidences, existing pediatric transfusion guidelines can help pediatric care providers in their decisions related to component transfusion.

References

Dec 1, 1992·Journal of Cardiothoracic and Vascular Anesthesia·M D Hershey, D D Glass
May 1, 1995·Journal of Pediatric Surgery·H KemmotsuM Yamashita
May 1, 1994·Transfusion·L StehlingL T Goodnough
Feb 13, 2001·British Journal of Haematology·J Ramasethu, N Luban
Feb 24, 2001·Seminars in Hematology·K Ohene-Frempong
Nov 8, 2002·Transfusion·Susan D RoseffCatherine S Manno
Mar 1, 2003·Vox Sanguinis·C P EngelfrietCécile Kaplan
Feb 27, 2004·British Journal of Haematology·Brenda E S GibsonG Turner

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Citations

Feb 26, 2013·British Journal of Haematology·Yaser A DiabNaomi L C Luban
Mar 5, 2010·Paediatric Anaesthesia·Gregory J Latham, Robert S Greenberg
Mar 23, 2015·Blood Reviews·Neil ShahLawrence Tim Goodnough
May 6, 2014·Indian Journal of Pediatrics·Shalini BahadurManjula Jain

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