Blood cultures for febrile patients in the acute care setting: too quick on the draw?

Journal of the American Academy of Nurse Practitioners
Barbara K ChesnuttRuth M Kleinpell

Abstract

To review the fever literature and determine how 38.3 degrees C was deemed the optimal fever threshold that predicts bacteremia. PubMed, MEDLINE, Cochrane database, and the Cumulative Index to Nursing and Allied Health. A temperature of 38.3 degrees C has come to be the threshold value that typically triggers diagnostic fever evaluation for bacteremia in hospitalized patients. Studies that define predictors of bacteremia provide conflicting results, and most bacteremia predictor models have not been externally validated. Therefore, current fever guidelines are based on consensus opinion rather than large clinical trials identifying a specific threshold with high sensitivity and a high negative predictive value. The use of a single temperature threshold of 38.3 degrees C for the prediction of bacteremia is not sufficient in all patients. Additional factors should be considered, including patient population, supporting clinical signs and symptoms, and the patient's medical history.

References

Oct 1, 1992·Journal of the American Geriatrics Society·D A WhitelawP A Willcox
Mar 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R R MuderA M Goetz
Sep 1, 1991·Journal of the American Geriatrics Society·S C CastleT T Yoshikawa
Jan 16, 1991·JAMA : the Journal of the American Medical Association·D W BatesT H Lee
Oct 1, 1990·Annals of Internal Medicine·D W BatesT H Lee
May 1, 1988·Archives of Internal Medicine·D E CravenW R McCabe
Feb 1, 1987·Annals of Internal Medicine·M D Aronson, D H Bor
Sep 24, 1982·JAMA : the Journal of the American Medical Association·R Gleckman, D Hibert
Jul 1, 1994·Intensive Care Medicine·K J SchwenzerC G Durbin
May 25, 1994·JAMA : the Journal of the American Medical Association·D PittetR P Wenzel
Sep 1, 1993·Journal of Clinical Epidemiology·B MozesH Halkin
Feb 1, 1996·American Journal of Respiratory and Critical Care Medicine·D PittetP M Suter
Mar 1, 1996·Infectious Disease Clinics of North America·B A Cunha, K W Shea
Jul 1, 1996·QJM : Monthly Journal of the Association of Physicians·G R Jones, J A Lowes
Feb 1, 1996·Journal of General Internal Medicine·Y YehezkelliL Leibovici
Jul 14, 1999·Diagnostic Microbiology and Infectious Disease·G Maschmeyer
Sep 2, 1999·Critical Care Medicine·J D EdgeworthS J Eykyn
Aug 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J KlasterskyJ Talcott
Oct 6, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D W BentleyUNKNOWN Society for Healthcare Epidemiology of America
Feb 19, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Walter T HughesLowell S Young
Jan 17, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fabián JaimesFaber Machado
Mar 5, 2004·Intensive Care Medicine·R Phillip DellingerM M Levy
Mar 17, 2004·The American Journal of Cardiology·Alain G BertoniDavid C Goff
Mar 19, 2004·Journal of the American Podiatric Medical Association·Patricia A Cristofaro
Apr 20, 2004·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Management Guidelines Committee
Mar 19, 2005·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R San JuanJ J Rufilanchas
Apr 6, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mical PaulUNKNOWN TREAT Study Group
Mar 27, 2007·Annals of Emergency Medicine·Linda F McCaigMatthew J Kuehnert

❮ Previous
Next ❯

Citations

Sep 25, 2012·The Journal of Emergency Medicine·Rita Andersen LethBrian Kristensen
Dec 17, 2016·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Daisuke UchidaUNKNOWN Japanese InvestigatOrs with Innovative NeTwork about Kidney Disease (JOINT-KD)
Dec 4, 2010·Clinical Pediatrics·Lynn Herzog, Stephanie G Phillips
Mar 16, 2019·Diagnosis·Jessica Howard-AndersonRoswell Quinn
Dec 19, 2014·Annals of the Royal College of Surgeons of England·D F J DunneS W Fenwick

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved