Blood Cytokine Profile in Rats with Different Behavioral Characteristics after Metabolic Stress

Bulletin of Experimental Biology and Medicine
N V KirbaevaA V Vasil'ev

Abstract

Changes in the blood cytokine profile in rats with various parameters of behavior were studied under conditions of 5-day starvation not followed by the recovery period or with subsequent normalization of food intake. Metabolic stress had no effect on the content of most cytokines. The concentration of pro- and anti-inflammatory cytokines in blood plasma of rats was shown to increase significantly by the end of a 5-day recovery period after food deprivation. These changes in behaviorally passive specimens were more pronounced than in active animals. Therefore, differences in the strain of immune reactions in mammals with different prognostic resistance to extreme factors are most pronounced during the post-stress period. These data illustrate the necessity of an individual approach to studying the systemic organization of physiological functions under normal and pathological conditions.

References

Apr 29, 2004·Journal of the Experimental Analysis of Behavior·Susan SnycerskiAlan Poling
Dec 23, 2009·Bulletin of Experimental Biology and Medicine·S S PertsovA S Simbirtsev
Jul 18, 2012·Bulletin of Experimental Biology and Medicine·S S PertsovL S Kalinichenko
Apr 29, 2014·Bulletin of Experimental Biology and Medicine·N E SharanovaM M G Gapparov
Apr 29, 2014·Bulletin of Experimental Biology and Medicine·E V KoplikL S Kalinichenko
Apr 29, 2014·Bulletin of Experimental Biology and Medicine·L S KalinichenkoS S Pertsov
Dec 6, 2017·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Areej M AssafMaysaa Al-Binni

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