PMID: 11904029Mar 21, 2002Paper

Blood flow and ischemia within traumatic cerebral contusions

Neurosurgery
Gorm von OettingenJens Astrup

Abstract

To provide evidence of irreversible ischemia in cerebral contusions among patients with severe traumatic brain injuries and to clarify the potential viability of tissue in the pericontusional zone, quantitative regional cerebral blood flow (rCBF) measurements obtained with the xenon-enhanced computed tomographic method were correlated with the areas of contusions, by using image fusion. rCBF measurements obtained during the acute phase (mean, 2 d after injury; range, 0-10 d) were statistically correlated with the extent of tissue necrosis identified as focal atrophy on late follow-up computed tomographic scans (mean time after the xenon-enhanced computed tomographic cerebral blood flow investigation, 265 d; range, 30-1047 d). Seventeen patients exhibited 26 traumatic contusions. All contusions progressed to late focal atrophic areas on the follow-up computed tomographic scans. The rCBF values within the traumatic contusions ranged from 0.5 to 22.0 ml/100 g/min, with a mean of 5.9 +/- 5.9 ml/100 g/min. The contusions exhibited a specific rCBF profile, presenting as a core of severe lethal ischemia surrounded by variable but gradually increasing perfusion with increasing distance from the ischemic core. The ischemic profile of th...Continue Reading

References

Oct 1, 1977·Journal of Neurosurgery·J D MillerM J Rosner
May 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·R BullockJ H Adams
Mar 1, 1991·Journal of Neurosurgery·D W MarionH Yonas
Jan 1, 1985·British Journal of Anaesthesia·J D Miller
Jul 13, 1974·Lancet·G Teasdale, B Jennett
Nov 1, 1974·Archives of Neurology·J B North, S Jennett
Jan 1, 1967·Circulation Research·W D ObristH S Wang
Nov 1, 1981·Stroke; a Journal of Cerebral Circulation·J AstrupL Symon
Aug 1, 1980·AJR. American Journal of Roentgenology·J S MeyerS Nakajima
Jan 1, 1995·Acta neurochirurgica·T MathiesenG Edner
Nov 1, 1996·Journal of Neurosurgery·M R McLaughlin, D W Marion
Nov 11, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·W D ObristH Yonas
Apr 7, 2000·Journal of Neuroscience Methods·G von OettingenJ Astrup

❮ Previous
Next ❯

Citations

Jan 1, 2003·Journal of Neurosurgery·Sherman C SteinDouglas H Smith
Jan 30, 2004·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Helen M Bramlett, W Dalton Dietrich
Nov 28, 2007·Neuroradiology·Jean F SoustielMenashe Zaaroor
Oct 7, 2009·Journal of Neurotrauma·Susanne M SchwarzmaierNikolaus Plesnila
Dec 12, 2013·Journal of Neuroscience Research·José Luís Alves
Apr 13, 2004·Current Opinion in Critical Care·Jonathan P Coles
Oct 5, 2006·Current Opinion in Anaesthesiology·Roman Hlatky, Claudia S Robertson
Aug 13, 2011·Neuropathology and Applied Neurobiology·C VoigtM U Schuhmann
Jun 1, 2016·Frontiers in Human Neuroscience·Konstantinos I PapadimitriouEmmanuel M Drakakis
Nov 1, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Michelle L RogersMartyn G Boutelle
Sep 29, 2019·Stem Cells and Development·Samantha L DelaneyAllen L Ho
Mar 27, 2007·Intensive Care Medicine·Arturo ChieregatoEnrico Fainardi
Apr 19, 2007·British Journal of Neurosurgery·B SplavskiJ Legcević
Aug 18, 2010·Neurological Research·Leonardo Rangel-CastillaClaudia Robertson
Mar 21, 2007·Journal of Neurosurgery·Motoaki NakabayashiHiroki Tomita
Dec 9, 2008·Journal of Neurotrauma·Abel Po-Hao HuangSheng-Jean Huang
Jul 1, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Baptiste BalançaThomas Lieutaud
Mar 31, 2005·Journal of Neurosurgery·Martin EngströmCarl-Henrik Nordström
Mar 19, 2009·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jonathan P ColesDavid K Menon
Feb 3, 2012·Translational Stroke Research·Adam ChodobskiJoanna Szmydynger-Chodobska
May 23, 2008·Annals of Neurology·Christian DohmenUNKNOWN Co-Operative Study of Brain Injury Depolarisations (COSBID)
Jan 27, 2016·Der Nervenarzt·Katharina Hackenberg, A Unterberg
Nov 26, 2009·Journal of Neurotrauma·Cornelia LundbladPeter Bentzer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.