PMID: 10728307Mar 23, 2000

Blood flow distributions by microsphere deposition methods

Cardiovascular Research
Frits W Prinzen, James B Bassingthwaighte

Abstract

The art and science of the use of deposition markers for the estimation of blood flow distributions throughout the body and within organs is reviewed. Development of diffusible tracer techniques started 50 years ago. Twenty years later, radioactive 15 micron microspheres became the standard marker. Early studies on small animals, fetal sheep in 1967 and rats in 1976, provoked much of the technical development. Needs for avoiding the use of radioactivity, for having long lasting labels, and for providing higher spatial resolution, are driving the continuing exploration of newer techniques using colored and fluorescent microspheres and molecular deposition markers. Strengths and weaknesses of the various methods are compared.

References

Mar 1, 1979·Pharmacological Research Communications·A QuintanaA Bonaccorsi
Apr 30, 1979·Pflügers Archiv : European journal of physiology·J R HalesA A Fawcett
Jul 1, 1977·Progress in Cardiovascular Diseases·M A HeymannA M Rudolph
Sep 1, 1977·Scandinavian Journal of Clinical and Laboratory Investigation·S WetterlinI Ahlgren
Nov 5, 1976·Pflügers Archiv : European journal of physiology·J R HalesA A Fawcett
Sep 1, 1975·The American Journal of Physiology·R G TancrediJames B Bassingthwaighte
Jul 1, 1992·Basic Research in Cardiology·N CicuttiH F Downey
May 1, 1990·Circulation Research·James B BassingthwaighteK A Krohn
Sep 1, 1989·Circulation Research·James B BassingthwaighteS A Roger
Jan 1, 1987·Biulleten' eksperimental'noĭ biologii i meditsiny·O S MedvedevV Iu Khalatov
Aug 1, 1985·Circulation Research·R B KingL B Rowell
Jul 1, 1985·Basic Research in Cardiology·Y NoseM Nakamura
Apr 1, 1974·Canadian Journal of Physiology and Pharmacology·K Rakusan, J Blahitka
Jan 1, 1995·Cardiovascular Research·J P HakkinenD R Knight
Oct 1, 1994·Cardiovascular Research·Frits W Prinzen, R W Glenny
Nov 1, 1995·Acta Physiologica Scandinavica·F GrundA Ilebekk
Sep 1, 1995·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·D D StapletonJames B Bassingthwaighte
Jun 1, 1997·Cardiovascular Research·T L MulderC E Blanco
Jan 15, 1999·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·D L LuchtelR W Glenny
Jan 1, 1961·Circulation Research·M N LEVY, J MARTINS DE OLIVEIRA

Citations

Jan 5, 2002·Basic Research in Cardiology·James B BassingthwaighteZ Li
Aug 24, 2012·Annals of Biomedical Engineering·James B BassingthwaighteKalyan C Vinnakota
Dec 15, 2012·Journal of Biomechanics·Jeroen van den WijngaardMaria Siebes
Aug 6, 2004·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ornella E Rimoldi, Paolo G Camici
May 9, 2003·The Annals of Thoracic Surgery·Marc A RuelWilliam E Cohn
Nov 7, 2009·Nature Protocols·Maria A Serrat
Dec 3, 2008·Journal of Biomechanical Engineering·Ashvinikumar V MudaliarThomas E Diller
Jul 23, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Roy JogiyaSven Plein
Dec 8, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Miranda FongYongge Liu
Jan 20, 2011·World Journal of Gastroenterology : WJG·Sebastiaan J HanssenMichael J Jacobs
Jun 15, 2011·World Journal of Gastrointestinal Surgery·Linas UrbanavičiusDonatas Venskutonis
Apr 30, 2009·Radiology·Marlies OostendorpWalter H Backes
Dec 2, 2011·Journal of Cardiovascular Translational Research·Marc StrikKevin Vernooy
Jul 5, 2011·Journal of Biomedical Optics·Garret MunchOlga Jilkina
Aug 19, 2007·The International Journal of Cardiovascular Imaging·Timothy F ChristianBabul Borah
Feb 13, 2016·Frontiers in Neurology·Judith BellapartJohn F Fraser
Aug 9, 2011·Ultrasound in Medicine & Biology·John M HudsonPeter N Burns
Feb 18, 2010·Drug Discovery Today. Disease Models·B A Coppola, J H Omens
Nov 4, 2009·International Journal of Heat and Mass Transfer·Patricia L RickettsThomas E Diller
Oct 31, 2006·Experimental Eye Research·Lin WangGeorge A Cioffi
Jul 3, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Dirk Ernst Johannes CleppienLaura M Schreiber
Nov 28, 2012·Atherosclerosis·Shamim LotfiBijan Modarai
Sep 3, 2014·Journal of Molecular and Cellular Cardiology·Nazanin HakimzadehMaria Siebes
May 13, 2015·Microvascular Research·Matthew SinclairNicolas Smith
Aug 16, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Marnie G SilversteinKylie Kavanagh
Apr 29, 2016·Upsala Journal of Medical Sciences·Leif JanssonPer-Ola Carlsson
Oct 16, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Andreas SchusterEike Nagel
Nov 20, 2015·BioMed Research International·Paloma Morillas-SendínBegoña Quintana-Villamandos
Jan 25, 2005·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·K De AngelisM C Irigoyen
Aug 19, 2009·Preventive Medicine·S Boyd EatonPhillip B Sparling
Jan 20, 2017·EJNMMI Research·Carlos VelascoJesus Ruiz-Cabello
Jan 24, 2018·American Journal of Physiology. Endocrinology and Metabolism·Eugenia Mata-GreenwoodLubo Zhang
Jul 12, 2018·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Olivier CoutureMickael Tanter
Jan 19, 2008·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Mikko LarsenAllen T Bishop
Dec 17, 2005·Physics in Medicine and Biology·M MarxenR M Henkelman
Sep 17, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·John StephensDouglas G Burrin
May 23, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Joan M GreveCharles A Taylor
Jun 13, 2006·American Journal of Physiology. Heart and Circulatory Physiology·M MarxenR M Henkelman
Sep 2, 2014·Journal of Synchrotron Radiation·Sang Joon LeeSung Yong Jung
Nov 16, 2002·News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society·Ulrich K M Decking
Jan 29, 2017·American Journal of Physiology. Heart and Circulatory Physiology·Julien I E Hoffman
Mar 22, 2013·Critical Care : the Official Journal of the Critical Care Forum·Antione G SchneiderRinaldo Bellomo
Jan 28, 2003·Journal of Cardiovascular Pharmacology·Coert Jozef ZuurbierCan Ince
Jul 18, 2000·Journal of Microencapsulation
Sep 7, 2000·Journal of Cardiovascular Pharmacology·C RicherJ F Giudicelli
Mar 3, 2020·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Babak SaraviFabian A Kari
Dec 13, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Johannes MartensLaura M Schreiber
Dec 24, 2004·European Heart Journal·Kevin VernooyFrits W Prinzen
Apr 17, 2020·Chemical Communications : Chem Comm·Jordan P HookerChristopher Barner-Kowollik
Sep 29, 2000·American Journal of Physiology. Heart and Circulatory Physiology·L M SchwartzJames B Bassingthwaighte
May 1, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Ulrich K M DeckingRobert S Balaban
Mar 3, 2020·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Ruud BuetersKendall S Frazier
Dec 25, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Kalyan C Vinnakota, James B Bassingthwaighte
Oct 6, 2017·American Journal of Physiology. Renal Physiology·Cesar A RomeroOscar A Carretero
Nov 10, 2018·Intensive Care Medicine Experimental·Judith BellapartJohn F Fraser
Nov 22, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Tada YipintsoiJames B Bassingthwaighte
Nov 20, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Liangdong ZhouYi Wang
Dec 4, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Bo-Wen ZhengJie Ren

Related Concepts

Cardiac Output
Diagnostic Techniques, Cardiovascular
Canis familiaris
Latex Spheres
Regional Blood Flow

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.