Blood flow in intracranial aneurysms treated with Pipeline embolization devices: computational simulation and verification with Doppler ultrasonography on phantom models

Ultrasonography
Anderson Chun On TsangKwok Wing Chow

Abstract

The aim of this study was to validate a computational fluid dynamics (CFD) simulation of flow-diverter treatment through Doppler ultrasonography measurements in patient-specific models of intracranial bifurcation and side-wall aneurysms. Computational and physical models of patient-specific bifurcation and sidewall aneurysms were constructed from computed tomography angiography with use of stereolithography, a three-dimensional printing technology. Flow dynamics parameters before and after flow-diverter treatment were measured with pulse-wave and color Doppler ultrasonography, and then compared with CFD simulations. CFD simulations showed drastic flow reduction after flow-diverter treatment in both aneurysms. The mean volume flow rate decreased by 90% and 85% for the bifurcation aneurysm and the side-wall aneurysm, respectively. Velocity contour plots from computer simulations before and after flow diversion closely resembled the patterns obtained by color Doppler ultrasonography. The CFD estimation of flow reduction in aneurysms treated with a flow-diverting stent was verified by Doppler ultrasonography in patient-specific phantom models of bifurcation and side-wall aneurysms. The combination of CFD and ultrasonography may con...Continue Reading

References

May 20, 1998·Ultrasound in Medicine & Biology·K V RamnarineJ Lubbers
Apr 17, 2008·Journal of Biomechanical Engineering·Matthew D FordDavid A Steinman
Jul 12, 2008·Medical & Biological Engineering & Computing·S K LamK W Chow
May 12, 2009·American Journal of Physiology. Heart and Circulatory Physiology·Philippe ReymondNikos Stergiopulos
Nov 13, 2010·AJNR. American Journal of Neuroradiology·J R CebralC M Putman
Aug 9, 2011·International Journal for Numerical Methods in Biomedical Engineering·Jr CebralCm Putman
Jan 24, 2012·AJNR. American Journal of Neuroradiology·D F Kallmes
Jan 17, 2013·Stroke; a Journal of Cerebral Circulation·Waleed BrinjikjiDavid F Kallmes
Apr 23, 2013·Annals of Biomedical Engineering·Trung B LeFotis Sotiropoulos
Jun 25, 2013·Ultrasound in Medicine & Biology·Simon S M LaiAlfred C H Yu
Jul 31, 2013·Journal of Biomechanics·Hernán G MoralesAlejandro F Frangi
Apr 11, 2014·International Journal for Numerical Methods in Biomedical Engineering·Juan R CebralDavid Kallmes
Jun 18, 2014·Ultrasonography·Whal Lee
Jul 21, 2014·Ultrasonography·Sung Ill Jang, Dong Ki Lee

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Citations

Jul 19, 2016·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Adrian J Y CheeAlfred C H Yu
Apr 27, 2017·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Ahmed E HusseinAli Alaraj
Dec 14, 2016·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Chung Kit HoAlfred C H Yu
Oct 12, 2016·Journal of Biomechanical Engineering·Ronak DholakiaBaruch B Lieber
Feb 28, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Ahmed E HusseinAli Alaraj
Oct 31, 2021·Computers in Biology and Medicine·Armin AbdehkakhaHui Meng
Dec 16, 2019·Neurosurgery·Georgios A MaragkosVitor Mendes Pereira
Nov 3, 2018··Daniil V. ParshinIuliia O. Kuianova

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