PMID: 8606624Jan 1, 1996Paper

Blood glucose and prolactin in hyperprolactinemic rats exposed to restraint and surgical stress

Life Sciences
F M ReisC C Coimbra

Abstract

The effects of chronic hyperprolactinemia on plasma prolactin (PRL) and glucose were investigated in male rats submitted to two different types of stress: restraint (60 min in a plastic tube) or surgery (laparotomy under ether anesthesia). Hyperprolactinemia was induced by grafting one homologous pituitary gland under the kidney capsule. Restraint stress induced a marked increase of plasma PRL of control rats with a peak at 15 min (increase of 403%), but did not change the PRL levels of hyperprolactinemic rats. Plasma glucose levels of both groups were elevated by restraint stress at 5 min (control, 26%; grafted, 63%), and remained above basal levels during the whole experimental period. However, at 15 min the hyperglycemic response of the grafted rats was higher than that of control rats (p<0.05). Surgical stress induced a 204% increase of plasma PRL at 5 min in the control group, but failed to induce alterations of PRL in the hyperprolactinemic group. Plasma glucose was remarkably elevated at 15 min both in control (138%) and grafted (124%) rats after surgery, producing a hyperglycemic response much more intense than that induced by restraint. Grafted rats presented hyperglycemia during all the experimental period, whereas co...Continue Reading

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Citations

Jul 11, 2002·European Journal of Pharmacology·Trino BaptistaSerge Beaulieu
Mar 27, 2001·Pharmacology, Biochemistry, and Behavior·A Ribeiro-de-OliveiraC C Coimbra
Jun 16, 1999·Progress in Neuro-psychopharmacology & Biological Psychiatry·T BaptistaL Hernández
Aug 12, 1999·Acta Psychiatrica Scandinavica·T Baptista
May 12, 1997·Journal of the Autonomic Nervous System·R B FóscoloC C Coimbra
Jan 28, 1999·Veterinary Pathology·L A Bolton, L Munson
Apr 18, 2018·Stress : the International Journal on the Biology of Stress·Antônio Ribeiro-OliveiraKevin C J Yuen
Jan 5, 2002·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·T BaptistaL Hernàndez
Aug 21, 2013·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Antônio Ribeiro-OliveiraMárta Korbonits

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