Abstract
Several studies have shown that elevated blood lead (Pb) levels in children are associated with decreased growth. Among 139 children aged 1 to 10 years (66 male, 73 female) who attended a Pb clinic in Dallas, Texas, growth was decreased by 1.6 cm in height, 1.4 kg in weight, and 0.6 cm in head circumference for each 10 μg/dl increase in blood Pb. Consistent with previously reported effects of Pb, several clinical symptoms (hearing deficit, dental problems, hyperactivity) were increased in frequency among children with high blood Pb levels (X̄Pb = 34.6 μg/dl ± 5.6) compared to the children in the low Pb level group (X̄Pb = 11.9 μg/dl ± 3.3). Interestingly, pica was significantly increased in frequency among children in the high Pb group, indicating oral consumption of non-food matter was a major source of Pb intoxication. These results suggest that increased Pb level is an important risk factor for growth deficits in children.
References
Mar 15, 1975·Lancet·A D BeattieG T Steward
Sep 1, 1978·The Journal of Pediatrics·H K SachsB Rayson
Mar 29, 1979·The New England Journal of Medicine·H L NeedlemanP Barrett
Dec 1, 1976·The Journal of Pediatrics·P J LandriganI H Von Lindern
Oct 1, 1975·The Journal of Pediatrics·B de la Burdé, M L Choate
May 1, 1987·Neurotoxicology and Teratology·C B ErnhartA W Wolf
Dec 1, 1988·Current Problems in Pediatrics·H L Needleman
Dec 1, 1988·Birth·M Rabinowitz
Sep 1, 1988·Journal of Epidemiology and Community Health·N R WiggR J Roberts
Apr 23, 1987·The New England Journal of Medicine·D BellingerM Rabinowitz
Mar 1, 1987·International Journal of Epidemiology·S J PocockM A Smith
May 1, 1987·Archives of Environmental Health·J Schwartz, D Otto
Mar 1, 1986·Journal of Epidemiology and Community Health·A J McMichaelP D Clark
Sep 1, 1986·Archives of Environmental Health·C B ErnhartR J Sokol
Jan 1, 1986·American Journal of Physical Anthropology·M C LauwersJ Verheyden
Oct 28, 1972·Lancet·O DavidK Voeller
Sep 1, 1974·Journal of Dental Research·J W HabercamH W Croft
Dec 1, 1972·The Journal of Pediatrics·B De la Burdé, M S Choate
Sep 11, 1970·Science·R M SauerF M Garner
Sep 1, 1980·Mutation Research·G B GerberP Jacquet
Citations
Oct 25, 2006·Annals of Human Biology·Z IgnasiakR M Malina
Dec 19, 2018·International Journal of Environmental Research and Public Health·Robert ReillyBert B Little
Jan 1, 1992·Chromosoma·W MesserB Woelker
Apr 1, 1994·Immunological Reviews·C I SmithL Hammarström
Apr 17, 2007·Nature Reviews. Microbiology·Melissa L Mott, James M Berger
Jun 24, 2008·Critical Reviews in Biochemistry and Molecular Biology·Karl E Duderstadt, James M Berger
Aug 23, 2011·American Journal of Human Biology : the Official Journal of the Human Biology Council·Emanuele Sanna, Elisabetta Vallascas
Oct 31, 2017·Annals of Human Biology·Bert B LittleDavid L Wiegman
Jul 7, 2007·Annals of Human Biology·Zosia IgnasiakB B Little
Apr 22, 2009·Annals of Human Biology·B B LittleT Gratton
Aug 18, 2010·Biological Trace Element Research·Yongpeng TongJianmin Chen
Nov 11, 2008·American Journal of Human Biology : the Official Journal of the Human Biology Council·Lawrence M SchellElaine E Schulte
May 26, 2018·PloS One·Mohammad Jyoti RaihanTahmeed Ahmed
May 4, 2012·American Journal of Human Biology : the Official Journal of the Human Biology Council·Teresa SławińskaRobert M Malina