Blood lead levels, pulmonary function and agility in Polish schoolchildren

Annals of Human Biology
Bert B LittleDavid L Wiegman

Abstract

Reduced vital capacity (VC) and forced vital capacity (FVC) are associated with lead (Pb) exposure. The objective of this study is to analyse the effects of Pb on FVC and the shuttle run performance. Data were available for 184 male and 189 female Polish schoolchildren aged 10-15 years. Regression analysis was performed of shuttle run performance (dependent) on Pb and FVC. Shuttle run time increased by 1.75 (± 0.77) and 1.97 (± 0.77) seconds for each 10 µg/dL increase in Pb blood among males and females, respectively. Higher shuttle run times indicate poorer performance. Average unadjusted blood Pb level in the sample was 5.27 μg/dL (± 0.19 SE) and 3.82 μg/dL (± 0.10 SE), respectively. Path analysis was used to assess the association of Pb level with shuttle run time. Blood Pb had a significant negative effect on VC (B= -13.60 ± 3.28 [SE], p < 0.0001) and FVC (B = -13.08 ± 3.27, p < 0.0001). FVC had a small but significant effect on shuttle run time (B = -0.04 ± 0.007, p < 0.0001). Pb had a significant effect on the residual of shuttle run time among males (B = 1.59 ± 0.75, p < 0.03) and females after the effect of FVC was removed (B = 1.49 ± 0.73, p < 0.04). Thus, Pb had direct and indirect effects that increased shuttle run t...Continue Reading

References

Sep 1, 1988·Regulatory Toxicology and Pharmacology : RTP
Jun 1, 1994·Bulletin of Environmental Contamination and Toxicology·P SalovskyR Marev
May 1, 1993·Archives of Environmental Health·H MuñozM Hernandez-Avila
Apr 9, 1999·Journal of Vascular Surgery·J A Rodriguez-LopezE B Diethrich
Jul 25, 2000·Archives of Environmental Health·M I Azcona-CruzM Romero-Placeres
Aug 29, 2002·Archives of Pediatrics & Adolescent Medicine·Scott N MyersHelen J Binns
Aug 18, 2004·International Journal of Clinical Practice·C BagciB Cengiz
Jul 9, 2005·Environmental Health Perspectives·Christine L M JosephChristine Cole Johnson
Feb 21, 2008·Biological Trace Element Research·Jin-Young MinDomyung Paek
Apr 15, 2008·Arhiv za higijenu rada i toksikologiju·Saso StoleskiJordan Minov
Jan 5, 2012·Chest·Matthew D Jankowich, Sharon I S Rounds
May 4, 2012·American Journal of Human Biology : the Official Journal of the Human Biology Council·Teresa SławińskaRobert M Malina
Dec 19, 2012·Journal of Occupational and Environmental Medicine·Lina MadaniyaziXiaochuan Pan
Feb 12, 2013·Iranian Red Crescent Medical Journal·Mohammad Reza KhazdairSeyed Saleh Tabatabaie
Jan 1, 1990·American Journal of Human Biology : the Official Journal of the Human Biology Council·B B LittleP H Buschang

❮ Previous
Next ❯

Citations

Jun 23, 2019·Biological Trace Element Research·Zhenzhen PanLing Li
Oct 19, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Anatoly V SkalnyAlexey A Tinkov
Jul 25, 2021·International Journal of Environmental Research and Public Health·Jessica M MadrigalMaria Argos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.