PMID: 2496249Mar 1, 1989Paper

Blood levels of water-soluble vitamins in pediatric patients on total parenteral nutrition using a multiple vitamin preparation

JPEN. Journal of Parenteral and Enteral Nutrition
E MarinierJ Navarro

Abstract

Although guidelines for the parenteral use of vitamin preparations in pediatric patients have been published, there are very limited data on the efficiency of these preparations and on the exact needs of infants and children on total parenteral nutrition (TPN). We report here an open, prospective, study of the blood levels of water-soluble vitamins in infants and children on TPN before and during supplementation with a new water-soluble multivitamin formula containing per vial unit: B1, 3 mg; B2, 3.6 mg; B6, 4 mg; niacin, 40 mg; pantothenate, 15 mg; ascorbate, 100 mg; biotin, 60 micrograms; folic acid, 400 micrograms; B12, 5 micrograms. Thirteen children, 9 months to 15 yr old, on home TPN for 1.5 months to 7 yr, and 17 hospitalized infants and children, 1 week to 15 yr old, receiving TPN were studied for 2 weeks to 4 months. Daily doses were given according to age: 1/2 vial if less than 18 months; 1 vial if greater than 18 months and less than 10 years; 1.5 vials if greater than 10 years. Assays for B1, B2, biotin, niacin, plasma and red blood cell (RBC) folates were performed by microbiologic methods, B12 was measured by radioimmunoassay. During the study, B1 levels were consistently above the upper limit of the normal range,...Continue Reading

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Citations

Sep 27, 2003·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·L Cynober
Apr 1, 1990·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·C RicourD Pellerin
Nov 11, 2008·Journal of Animal Science·S B SmithJ E Sawyer
Dec 19, 2017·Journal of Animal Physiology and Animal Nutrition·V ZancanelaM F Z Ferreira

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