Blood macrophage colony-stimulating factor and thrombin-antithrombin III complex concentrations in pregnancy and preeclampsia

The American Journal of the Medical Sciences
M HayashiY Yaoi

Abstract

Macrophage colony-stimulating factor (M-CSF) is a characteristic cytokine that plays an essential role in placenta maintenance, and thrombin-antithrombin III complex (TAT) is a hemostatic marker that is remarkably altered both in normal pregnancy and in preeclampsia. The present study was designed in order to show various levels of M-CSF and TAT in pregnancies. Peripheral blood was collected from 49 subjects, of whom 31 were normal pregnant women consisting of the four groups (namely 10th, 20th, 30th, and 38th weeks of gestation), 13 were preeclamptic pregnant women (37th week of gestation; mean blood pressure, 158/99 mm Hg), and 5 were nonpregnant controls. We compared blood M-CSF and TAT levels among them. Results showed that blood M-CSF and TAT levels increased significantly with gestational age. Furthermore, the ratio of increase in M-CSF was significantly lower than that in TAT in normal pregnant women compared with controls. In contrast, the ratio of increase in M-CSF was significantly higher than that in TAT in preeclamptic women compared with normal pregnant women. These results concerning the ratio of increase in M-CSF and TAT have not been reported. These findings show that M-CSF level increases significantly in preec...Continue Reading

References

Oct 1, 1991·Current Opinion in Immunology·J W Pollard
Jan 1, 1991·Gynecologic and Obstetric Investigation·T TeraoY Takeda
Jun 1, 1990·British Journal of Obstetrics and Gynaecology·A ReinthallerG Tatra
Jan 1, 1989·American Journal of Obstetrics and Gynecology·K de BoerP E Treffers
Jan 1, 1985·Methods in Enzymology·E R Stanley
Jun 5, 1987·Science·S C Clark, R Kamen
Mar 1, 1995·Clinical and Laboratory Haematology·D P TsakonasA H Goldstone
Mar 1, 1994·British Journal of Haematology·V PraloranM F Naud

❮ Previous
Next ❯

Citations

Jul 23, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M HayashiT Ohkura
Apr 23, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Masatoshi HayashiTakeyoshi Ohkura
May 19, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·A-S Ducloy-Bouthors
Mar 9, 2002·American Journal of Reproductive Immunology : AJRI·Masatoshi HayashiNoriyuki Inaba
Jul 18, 2002·The American Journal of the Medical Sciences·Masatoshi HayashiTakeyoshi Ohkura
Oct 13, 2006·The American Journal of the Medical Sciences·Masatoshi HayashiNoriyuki Inaba
Feb 25, 2005·American Journal of Reproductive Immunology : AJRI·Masatoshi HayashiNoriyuki Inaba
Oct 19, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Zhengping WangJing He
Jun 24, 2004·American Journal of Reproductive Immunology : AJRI·Masatoshi HayashiNoriyuki Inaba
Feb 3, 2006·American Journal of Reproductive Immunology : AJRI·Masatoshi HayashiNoriyuki Inaba
May 16, 2007·American Journal of Reproductive Immunology : AJRI·Masatoshi HayashiNoriyuki Inaba
Feb 26, 2004·American Journal of Obstetrics and Gynecology·Masatoshi HayashiTakeyoshi Ohkura
Aug 9, 2008·International Immunopharmacology·Thomas G DouglassMartin R Jadus
Jun 24, 2008·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Offer ErezChong Jai Kim
Nov 25, 2003·American Journal of Obstetrics and Gynecology·Masatoshi HayashiNoriyuki Inaba

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.