Blood management in patients with deep prosthetic hip and knee infections.

Orthopedics
Gwo-Chin Lee, Fred D Cushner

Abstract

Patients undergoing treatment for infected hip and knee replacements often have significant blood loss and require allogeneic blood transfusions. In the setting of sepsis, traditional methods of blood management such as preoperative blood donations, cell savers, and reinfusion drains are contraindicated. Pharmacologic agents can minimize transfusion requirements by increasing erythropoiesis, or minimize perioperative blood loss. This article reviews the use of these agents in the management of patients with deep prosthetic hip and knee infections.

References

Feb 1, 1992·Journal of Cardiothoracic and Vascular Anesthesia·D Royston
Jun 1, 1991·Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·K H WollinskyM Weindler
Aug 1, 1994·Anesthesiology·S M KasperJ Rütt
Sep 1, 1994·British Journal of Anaesthesia·C M ThorpeM Logan
Oct 1, 1995·The Journal of Bone and Joint Surgery. American Volume·K L Garvin, A D Hanssen
May 1, 1995·The British Journal of Surgery·H J Nielsen
Feb 1, 1995·Transfusion·E C VamvakasM Cabanela
Jun 27, 1996·The New England Journal of Medicine·G B SchreiberJ J Korelitz
Sep 1, 1996·The American Journal of Medicine·N Blumberg, J M Heal
Jan 26, 1999·Clinical Orthopaedics and Related Research·E M KeatingM A Ritter
Feb 11, 1999·The Journal of Bone and Joint Surgery. American Volume·B E BierbaumR B Welch
Feb 16, 2000·British Journal of Anaesthesia·A J JansenK Jochmans
Sep 30, 2000·Archives of Orthopaedic and Trauma Surgery·K IdoS Kuriyama
Nov 22, 2001·Clinical Orthopaedics and Related Research·F D CushnerR L Barrack
Jan 17, 2002·International Orthopaedics·P Earnshaw
Feb 28, 2002·The Journal of Bone and Joint Surgery. American Volume·Jose A SalidoCristóbal Martínez
Apr 10, 2002·Transfusion Medicine Reviews·Eleftherios C Vamvakas
Jul 30, 2002·Anesthesia and Analgesia·Charles Marc SamamaPierre Coriat
Sep 7, 2002·Annals of the Royal College of Surgeons of England·S SharmaJ P Ivory
Nov 20, 2002·Clinical Orthopaedics and Related Research·Fred D CushnerW Norman Scott
Sep 11, 2003·Clinical Orthopaedics and Related Research·Gwo-Chin LeeArlen D Hanssen

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