Blood oxygenation level-dependent response to intragastric load of corn oil emulsion in conscious rats

Neuroreport
Tomokazu TsurugizawaKunio Torii

Abstract

The postingestive actions after intragastric or oronasal stimulation of fat have been well investigated. The blood oxygenation level-dependent (BOLD) signal changes, however, after intragastric load of corn oil emulsion have yet to be elucidated. Here, using functional magnetic resonance imaging, we investigated the BOLD signal response to gut corn oil emulsion in nonanesthetized rats. Intragastrically infused 7% corn oil emulsion induced a BOLD signal increase in several brain regions, including the bilateral amygdala, hippocampus and the ventral tegmental area. These results indicate that the limbic system responds to gut corn oil emulsion and that activation of this system could promote the reinforcing action for food with high fat content.

References

Sep 1, 1991·Brain Research Bulletin·G P Smith, D Greenberg
Jul 1, 1986·Journal of the Autonomic Nervous System·N Mei, L Garnier
Apr 29, 1998·Brain : a Journal of Neurology·L CornetteG A Orban
Dec 22, 1998·Brain Research. Brain Research Reviews·K C Berridge, T E Robinson
Jan 25, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·A RandichS S Bharaj
Apr 19, 2002·Brain : a Journal of Neurology·Daniel P Buxhoeveden, Manuel F Casanova
Dec 28, 2004·Nature Medicine·Akira HirasawaGozoh Tsujimoto
Jun 21, 2005·Journal of Neuroscience Methods·Jean A KingCraig F Ferris
Jul 2, 2005·Physiology & Behavior·Karen AckroffAnthony Sclafani
Jun 10, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Nu-Chu LiangRalph Norgren
Jun 3, 2008·Physiology & Behavior·Daniel H BessesenMarc A Cornier
Jul 4, 2008·Neuroreport·Tomokazu TsurugizawaKunio Torii
Mar 3, 2009·Gastroenterology·Tomokazu TsurugizawaKunio Torii

❮ Previous
Next ❯

Citations

Nov 22, 2012·The British Journal of Nutrition·Tomokazu TsurugizawaKunio Torii
Mar 24, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Anthony Sclafani, Karen Ackroff
Nov 5, 2010·Biological & Pharmaceutical Bulletin·Tomokazu Tsurugizawa, Kunio Torii
May 12, 2012·FEBS Letters·Shigenobu MatsumuraTohru Fushiki
Mar 6, 2012·Journal of Neuroscience Methods·Tomokazu TsurugizawaKunio Torii
Nov 28, 2013·Journal of Gastroenterology and Hepatology·Eiji NakamuraKunio Torii
Oct 10, 2013·The European Journal of Neuroscience·Tomokazu TsurugizawaHisayuki Uneyama
May 10, 2015·Current Diabetes Reports·Sophie C HamrFrank A Duca
Feb 2, 2012·Journal of Pharmacological Sciences·Akihiko KitamuraHisayuki Uneyama

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.