PMID: 234122Jan 1, 1975

Blood P50 calculated from a single measurement of pH, PO2, and SO2

Journal of Applied Physiology
A AbermanH Shubin

Abstract

P50 was calculated from a single measurement of pH, Po2, and So2 at a known temperature in 135 blood samples from 21 normal nonsmokers and eight patients. In the 92 blood samples with So2 between 20 and 90 per cent, the standard deviation of repeated calculated P50's on the same sample of blood at different So2 was plus or minus 1.0 Torr. Below So2 of 20 per cent and above So2 of 90 per cent, the standard deviations were plus or minus 5.5 and plus or minus 2.4 Torr, respectively. Combined measurement errors of plus or minus 1 Torr in Po2, plus or minus 1 percent in So2, plus or minus 0.01 in pH, and plus or minus 0.1 degree C in temperature are sufficient to explain the observed variation in calculated P50 in 90 per cent of 135 blood samples from 29 subjects and account for the greater observed variation at So2 less than 20 per cent and greater than 90 per cent.

References

Apr 1, 1984·Acta diabetologica latina·J Martins-SilvaP Sousa-Ramalho
Jan 1, 1997·International Journal of Clinical Monitoring and Computing·D J Doyle
Jan 1, 1976·British Journal of Haematology·M A LichtmanM Pogal
Apr 1, 1980·Anaesthesia·M A Thompson, M P Broadbent
Jan 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·A Coetzee, C Swanepoel
Aug 1, 1996·Intensive Care Medicine·H M Oudemans-van StraatenC P Stoutenbeek
Oct 1, 1982·Acta Anaesthesiologica Scandinavica·E Anjou-LindskogA Holmgren
Oct 31, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Georgia KostopanagiotouDennis Potter
Jan 12, 2013·Annals of Hematology·Fabienne L HuberKonrad E Bloch
Jan 1, 1991·Intensive Care Medicine·J A MyburghL I Worthley
Sep 1, 1982·Annals of Clinical Biochemistry·M J Roberts, P V Cole

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