PMID: 18195931Apr 15, 1983Paper

Blood platelet aggregometer: predicted effects of aggregation, photometer geometry, and multiple scattering

Applied Optics
P Latimer

Abstract

The in vitro aggregation of blood platelets is usually monitored with a visible light transmittance photometer (aggregometer). These cells in plasma are large (alpha = 2pi a/lambda approximately = 16) soft (m = 1.04) particles. The factors which significantly influence transmittance include the inherent scattering properties, multiple scattering, and photometer design. Now scattering theory and numerical methods for radiative transfer are used to survey how aggregation should influence transmittance as measured with various photometers. The results should help expand the analytical power of the transmittance photometer as a tool for monitoring aggregation. Evidence is also presented that scattering by aggregates of aerosol particles, which are of a higher relative refractive index, should also be adequately predicted by these approximate methods.

References

May 1, 1975·Journal of Theoretical Biology·P Latimer
Dec 1, 1969·Archives of Biochemistry and Biophysics·F D BryantB A Seiber
Dec 1, 1969·Archives of Biochemistry and Biophysics·F D BryantP Latimer
Jun 1, 1980·Scientific American·M B Zucker
Jan 1, 1982·Physiological Reviews·M M Frojmovic, J G Milton
Jan 1, 1982·Annual Review of Biophysics and Bioengineering·P Latimer
Jul 1, 1982·Applied Optics·P Latimer, F Wamble

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Citations

Dec 14, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Igor MindukshevJoerg Geiger
May 7, 2008·Bulletin of Experimental Biology and Medicine·M A MurinaV I Sergienko
Nov 14, 2001·Laboratory Investigation; a Journal of Technical Methods and Pathology·E Maurer-Spurej, D V Devine
May 26, 2017·Photosynthesis Research·Margaret Gwyn Latimer Govindjee

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