Blood pressure and atherosclerotic plaques in carotid, aortic and femoral arteries in elderly Finns with diabetes mellitus or impaired glucose tolerance

Journal of Human Hypertension
Ulla RajalaSirkka Keinänen-Kiukaanniemi

Abstract

The aim of the study was to evaluate the occurrence of atheromatous plaques in carotid, aortic and femoral arteries, focusing on blood pressure (BP). The study subjects consisted of 65-year-old Finns drawn from a population-based cohort. Ultrasonographic measurements were performed on 54 diabetic subjects, 97 subjects with impaired glucose tolerance (IGT) and 57 normoglycaemic subjects (NGT). High systolic BP (SBP) was defined as >or=160 mmHg and high diastolic BP as >or=95 mmHg. High pulse pressure (PP) was defined as the highest tertile (>or=75 mmHg) of PP and high mean BP (MBP) as the highest tertile (>or=111 mmHg) of MBP. The prevalence of atheromatous plaques was 77% (160/208) in carotid arteries, 94% (195/208) in aorta and 77% (161/208) in femoral arteries. A total of 64% (134/208) of the subjects had plaques in both carotid and femoral arteries, and they were compared with those who had plaques in 0-1 of these arteries. In addition to male gender and long-lasting smoking, the occurrence of plaques in both carotid and femoral arteries were associated with high SBP and high MBP. According to the results of multiple regression analyses, the adjusted odds ratio for plaques in both carotid and femoral arteries was 3.1 (95% CI...Continue Reading

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Citations

Aug 16, 2005·Diabetes Research and Clinical Practice·Ulla RajalaSirkka Keinänen-Kiukaanniemi
May 18, 2006·Journal of Internal Medicine·Y Z BaggerUNKNOWN Prospective Epidemiological Risk Factors Study Group
Jun 10, 2010·Journal of Clinical Periodontology·Pekka YlöstaloMatti Knuuttila
Jul 1, 2020·Terapevticheskiĭ arkhiv·E V SurkovaA V Naminov

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