Blood pressure and heart rate variability and baroreflex sensitivity before and after brain death

Journal of Neurology, Neurosurgery, and Psychiatry
F ConciPaolo Castiglioni

Abstract

To evaluate spontaneous blood pressure and heart rate variability and spontaneous baroreflex sensitivity before and after brain death. Spontaneous variability of arterial blood pressure and heart rate-estimated by power spectra of systolic (SBP) and diastolic blood pressure (DBP) and pulse interval (PI)-and spontaneous baroreflex sensitivity (BRS)-estimated by the alpha index and the sequence technique-were evaluated in 11 patients twice: shortly before and 1 hour after the onset of brain death. Significant spectral changes occurred after brain death: a general power reduction in PI spectra; a shift of SBP, DBP and PI powers toward the lower frequencies, resulting in a greater slope of the "1/f" spectral trends; and a marked reduction of SBP and DBP powers (-93%) and of SBP-PI coherence (-63%) at 0.1 Hz. The estimated average BRS was relatively high before brain death (around 11 ms/mm Hg), and fell close to 0 or even was not detectable at all after brain death. Parameters describing spontaneous blood pressure and heart rate variability and indexes reflecting the baroreflex function, which were relatively normal up to a few hours before brain death, underwent marked changes with the onset of brain death. All the changes found ar...Continue Reading

References

Aug 1, 1991·Circulation·A MallianiS Cerutti
May 1, 1991·Medical & Biological Engineering & Computing·R E Challis, R I Kitney
Sep 1, 1989·Electroencephalography and Clinical Neurophysiology·P CrennaL Boselli
Jun 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·F ConciL Boselli
Jun 1, 1973·Neurology·L P Ivan
Feb 1, 1995·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·V NovakR Schondorf
Aug 1, 1993·Journal of the Autonomic Nervous System·Y KitaR Takeda
Feb 1, 1993·Critical Care Medicine·B GoldsteinP D Woolf
Feb 1, 1996·Critical Care Medicine·B GoldsteinP D Woolf

❮ Previous
Next ❯

Citations

Oct 3, 2002·Current Opinion in Critical Care·Yi Gang, Marek Malik
Dec 13, 2007·The Journal of Trauma·William P RiordanJohn A Morris
Mar 28, 2009·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·M Di RienzoP Castiglioni
Nov 14, 2007·PLoS Computational Biology·Sven ZenkerGilles Clermont
Mar 11, 2011·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak, William L Lanier
Jun 15, 2006·Journal of Medical Engineering & Technology·D SinghK K Deepak
Aug 3, 2002·The Journal of Physiology·Michael A Cohen, J Andrew Taylor
Oct 16, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yazmina Machado-FerrerYanín Machado
May 4, 2010·Respiratory Physiology & Neurobiology·Andry Van de LouwFrançois Cottin
Dec 2, 2006·Prenatal Diagnosis·M R OrtizJ C Echeverría
Sep 12, 2007·Anaesthesia·M J Harrison, C W Connor
Dec 27, 2005·Progress in Neurobiology·Julie Y H ChanSamuel H H Chan
Apr 4, 2015·BMJ Case Reports·Calixto MachadoAdam Schiavi
Oct 9, 2004·Blood Pressure Monitoring·Yu-Cheng KuoYuh-Ying Lin Wang
Jul 16, 2004·Physiological Measurement·Dilbag SinghKishore K Deepak
Feb 14, 2019·Brain Injury : [BI]·Mario Estévez-BáezEduardo Arrufat-Pié
Jan 5, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Hiroshi MannojiHiroyuki Tsutsui
Apr 29, 2006·Journal of Applied Physiology·Gianfranco ParatiPaolo Castiglioni
Sep 21, 2013·Journal of Animal Science·T M Casey-TrottT M Widowski
Jan 15, 2016·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Sun-Ting TsaiTzay-Ming Hong
Jun 4, 2020·Journal of the Intensive Care Society·Brian W JohnstonIngeborg D Welters
Oct 29, 2014·Journal of Animal Science·T M Casey-TrottT M Widowski
Jan 25, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Andreas R SchwerdtfegerGert Pfurtscheller
Aug 8, 2006·Journal of Applied Physiology·J Andrew Taylor, Péter Studinger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Neurosurgical Anesthesiology
Abhik K Biswas, John F Summerauer
Current Treatment Options in Cardiovascular Medicine
Sanjay Dandamudi, Horng H Chen
© 2021 Meta ULC. All rights reserved