Blood pressure and lipid management fall far short in persons with type 2 diabetes: results from the DIAB-CORE Consortium including six German population-based studies.

Cardiovascular Diabetology
Ina-Maria RückertChrista Meisinger

Abstract

Although most deaths among patients with type 2 diabetes (T2D) are attributable to cardiovascular disease, modifiable cardiovascular risk factors appear to be inadequately treated in medical practice. The aim of this study was to describe hypertension, dyslipidemia and medical treatment of these conditions in a large population-based sample. The present analysis was based on the DIAB-CORE project, in which data from five regional population-based studies and one nationwide German study were pooled. All studies were conducted between 1997 and 2006. We assessed the frequencies of risk factors and co-morbidities, especially hypertension and dyslipidemia, in participants with and without T2D. The odds of no or insufficient treatment and the odds of pharmacotherapy were computed using multivariable logistic regression models. Types of medication regimens were described. The pooled data set comprised individual data of 15, 071 participants aged 45-74 years, including 1287 (8.5%) participants with T2D. Subjects with T2D were significantly more likely to have untreated or insufficiently treated hypertension, i.e. blood pressure of > = 140/90 mmHg (OR = 1.43, 95% CI 1.26-1.61) and dyslipidemia i.e. a total cholesterol/HDL-cholesterol ra...Continue Reading

References

Nov 1, 1994·Annals of Internal Medicine·B KinosianG Garland
Oct 1, 1993·Journal of Diabetes and Its Complications·C Chukwuma, J Tuomilehto
Jul 28, 1999·Clinical and Experimental Hypertension : CHE·C E Mogensen
Apr 17, 2001·Hypertension·J R SowersE D Frohlich
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Jul 17, 2001·Journal of Internal Medicine·P T Sawicki, A Siebenhofer
May 22, 2002·JAMA : the Journal of the American Medical Association·Joshua A BeckmanPeter Libby
Jun 13, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·B HedbladL Janzon
May 15, 2003·Diabetes & Metabolism·G CharpentierUNKNOWN ESPOIR Diabetes Study Investigators
Jun 28, 2003·BMJ : British Medical Journal·N J Wald, M R Law
Dec 6, 2003·Hypertension·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Mar 17, 2004·BMJ : British Medical Journal·Bryan WilliamsUNKNOWN BHS guidelines working party, for the British Hypertension Society
Apr 13, 2004·Journal of Hypertension·Arya M SharmaUNKNOWN HYDRA Study Group
Jun 9, 2004·Blood Pressure·U Muscha SteckelingsUNKNOWN HYDRA Study Group
Nov 10, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Lauren C BrownFinlay A McAlister
Mar 2, 2006·Journal of Hypertension·Christa MeisingerJan Lüdemann
Jun 27, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·B BischoffUNKNOWN DETECT Study-Group
Jul 28, 2006·Current Medical Research and Opinion·Rainer Düsing
Feb 5, 2008·Patient Education and Counseling·Koula G AsimakopoulouCharles Fox
Aug 5, 2008·Journal of Neurology·Mechtild M VennemannKlaus Berger
Feb 20, 2010·International Journal of Epidemiology·Henry VölzkeWolfgang Hoffmann
Mar 17, 2010·The New England Journal of Medicine·William C CushmanFaramarz Ismail-Beigi
Mar 17, 2010·The New England Journal of Medicine·Henry N GinsbergRobert P Byington
Jun 12, 2010·Diabetic Medicine : a Journal of the British Diabetic Association·H K BertholdI Gouni-Berthold
Oct 30, 2010·Primary Care Diabetes·Johan WensHans Vandenberghe
Jan 14, 2011·Diabetes Care·UNKNOWN American Diabetes Association
Feb 11, 2011·Diabetes/metabolism Research and Reviews·Reneé G StarkUNKNOWN KORA Study Group
Feb 15, 2011·International Journal of Clinical Practice·C J Bailey, M Kodack
Apr 7, 2011·The Journal of Clinical Hypertension·Mariela Glandt, Zachary T Bloomgarden
Jun 23, 2011·JAMA : the Journal of the American Medical Association·David PreissKausik K Ray
Sep 15, 2011·Vascular Health and Risk Management·Sandra J Lewis
Oct 22, 2011·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·M SchunkR Holle
Jan 11, 2012·Archives of Internal Medicine·Annie L CulverYunsheng Ma
Jan 12, 2012·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Pamela B DeGuzmanGeorge A Beller

❮ Previous
Next ❯

Citations

Nov 7, 2015·Journal of Diabetes Investigation·Mohsen JanghorbaniMasoud Amini
Oct 7, 2014·Cardiovascular Diabetology·Antonysunil AdaikalakoteswariPonnusamy Saravanan
Mar 11, 2015·PloS One·Li-Ting HoUNKNOWN Taiwanese Secondary Prevention for patients with AtheRosCLErotic disease (T-SPARCLE) Registry Investigators
Jan 24, 2018·Cardiovascular Diabetology·Roland E SchmiederUNKNOWN DIALOGUE study group
Feb 11, 2015·American Journal of Hypertension·Mark A EspelandUNKNOWN ACCORD Study Group
Aug 4, 2015·Journal of Hypertension·Iris WalravenGiel Nijpels
May 9, 2021·Environmental Science and Pollution Research International·Thoria Donia, Abeer Khamis

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

SAS

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.