PMID: 3820493Apr 3, 1987Paper

Blood pressure and metabolic effects of calcium supplementation in normotensive white and black men

JAMA : the Journal of the American Medical Association
R M LyleM H Weinberger


A randomized, double-blind, placebo-controlled trial was conducted to examine the effect of calcium supplementation on blood pressure in normotensive black (n = 21) and white (n = 54) men, aged 19 to 52 years. After a four-week baseline period of weekly blood pressure measurement, subjects were randomly assigned within racial groups to either a treatment (calcium, 1500 mg/d) or placebo group for a 12-week period. During the experimental period, multiple blood pressure measurements were taken every two weeks in both the seated and supine positions, using a random baseline sphygmomanometer. A repeated-measures analysis of covariance yielded a modest but significantly lower seated mean arterial pressure in the treatment group compared with the control group, but no differences between the races. Results were similar for supine blood pressure. Calcium supplementation, in comparison with placebo, resulted in lower mean arterial pressure in normotensive white and black men during a 12-week period. The overall blood pressure-lowering effect was not correlated with the response of serum levels of total and ionized calcium, total inorganic phosphorus, or parathyroid hormone, or overnight urinary electrolyte values.


Sep 1, 1989·American Journal of Public Health·C L MelbyR M Lyle
Dec 1, 1992·Journal of Clinical Pharmacy and Therapeutics·M M Rumore
Apr 12, 2000·Journal of the American College of Nutrition·G D MillerD A McCarron
Jan 1, 1989·Journal of the American College of Nutrition·T J Moore
Jan 1, 1990·Clinical and Experimental Hypertension. Part A, Theory and Practice·J G Fodor, A Chockalingam
Jul 1, 1990·Current Problems in Pediatrics·C L Kien
Jan 1, 1990·Preventive Medicine·R J HavlikJ C Christian
Jun 1, 1992·International Journal of Cardiology·R Schleiffer
Nov 1, 1987·The Journal of School Health·C L MelbyD L Corrigan
Feb 1, 1989·Kidney International·D A McCarron
Aug 1, 1991·Annals of Medicine·H Karppanen
Oct 30, 1987·The American Journal of Cardiology·M H Walczyk, D A McCarron
Oct 1, 1988·American Journal of Health Promotion : AJHP·C L MelbyG C Hyner
May 5, 2006·Journal of Human Hypertension·L A J van MierloJ M Geleijnse
Jul 1, 2015·The Cochrane Database of Systematic Reviews·Gabriela CormickJosé M Belizán
Apr 21, 2006·The Cochrane Database of Systematic Reviews·H O DickinsonJ Mason
Nov 1, 1989·Circulation·J C WittemanC H Hennekens
Dec 4, 1998·Stroke; a Journal of Cerebral Circulation·P B Gorelick
Feb 1, 1990·Journal of the American College of Nutrition·M B PamnaniF J Haddy
Dec 1, 1989·Journal of the American College of Nutrition·F C LuftC D Morris

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.