Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort.

Environmental Health Perspectives
Shohreh F FarzanMargaret R Karagas

Abstract

Inorganic arsenic exposure has been related to the risk of increased blood pressure based largely on cross-sectional studies conducted in highly exposed populations. Pregnancy is a period of particular vulnerability to environmental insults. However, little is known about the cardiovascular impacts of arsenic exposure during pregnancy. We evaluated the association between prenatal arsenic exposure and maternal blood pressure over the course of pregnancy in a U.S. The New Hampshire Birth Cohort Study is an ongoing prospective cohort study in which > 10% of participant household wells exceed the arsenic maximum contaminant level of 10 μg/L established by the U.S. EPA. Total urinary arsenic measured at 24-28 weeks gestation was measured and used as a biomarker of exposure during pregnancy in 514 pregnant women, 18-45 years of age, who used a private well in their household. Outcomes were repeated blood pressure measurements (systolic, diastolic, and pulse pressure) recorded during pregnancy. Using linear mixed effects models, we estimated that, on average, each 5-μg/L increase in urinary arsenic was associated with a 0.15-mmHg (95% CI: 0.02, 0.29; p = 0.022) increase in systolic blood pressure per month and a 0.14-mmHg (95% CI: 0....Continue Reading

References

May 1, 1991·Journal of the American Academy of Child and Adolescent Psychiatry·D P Farrington
Dec 23, 1993·The New England Journal of Medicine·A SagieD Levy
Nov 1, 1995·British Journal of Obstetrics and Gynaecology·H NisellE Pettersson
Jan 4, 1997·Lancet·D ChurchillD G Beevers
Feb 13, 1999·Paediatric and Perinatal Epidemiology·C C MatkinB Eskenazi
Nov 18, 2000·Analytical Chemistry·X C LeB Zheng
Jul 7, 2001·Early Human Development·J G RayM J Vermeulen
Nov 24, 2001·BMJ : British Medical Journal·H U IrgensR T Lie
Jan 17, 2002·The New England Journal of Medicine·R S VasanD Levy
May 23, 2002·International Journal of Hygiene and Environmental Health·Margaret R KaragasTor D Tosteson
Apr 19, 2003·BMJ : British Medical Journal·Brenda J WilsonW Cairns S Smith
Dec 4, 2003·Environmental Health Perspectives·Claudia HopenhaynDavid Kalman
Dec 4, 2003·American Journal of Epidemiology·Chris L BrysonCathy Critchlow
May 8, 2004·Paediatric and Perinatal Epidemiology·Xu Xiong, William D Fraser
Apr 5, 2005·The Medical Journal of Australia·Christine L RobertsDavid J Henderson-Smart
Dec 2, 2005·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Eyal SheinerAsher Bashiri
Nov 10, 2006·The American Journal of Clinical Nutrition·Mary V GambleJoseph H Graziano
May 8, 2007·Environment International·Shu-Li WangDennis P H Hsieh
May 19, 2007·Toxicology and Applied Pharmacology·Richard K KwokJudy L Mumford
Feb 27, 2008·Diabetes Care·Marshall W Carpenter
Aug 11, 2007·American Journal of Obstetrics and Gynecology·Jun ZhangGuillermo Carroli
Oct 17, 2007·Paediatric and Perinatal Epidemiology·Raymond S MillerMichelle A Williams
Jun 20, 2008·Lancet·Bryan WilliamsPeter Sever
Aug 22, 2008·The New England Journal of Medicine·Bjørn Egil VikseBjarne M Iversen
Nov 19, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·J Christopher StatesAaron Barchowsky
Jan 27, 2009·Toxicology and Applied Pharmacology·Chin-Hsiao Tseng
Sep 30, 2009·The American Journal of Medicine·Scott R YoderJohn D Bisognano
Dec 19, 2009·Environmental Health Perspectives·Chadi YazbeckGuy Huel
Feb 20, 2010·Obstetrics and Gynecology·Elisabeth B MagnussenPål R Romundstad
Aug 21, 2010·Journal of Hypertension·Rachel BakkerVincent Wv Jaddoe
Oct 14, 2010·Environmental Health Perspectives·Sultan AhmedRubhana Raqib
Sep 16, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kotaro FukushimaNorio Wake
Nov 24, 2011·Journal of Exposure Science & Environmental Epidemiology·Ellen M WellsFrank R Witter
Dec 6, 2011·Environmental Health Perspectives·Lalita N AbhyankarAna Navas-Acien
Dec 7, 2011·Proceedings of the National Academy of Sciences of the United States of America·Diane Gilbert-DiamondMargaret R Karagas

❮ Previous
Next ❯

Citations

Dec 31, 2016·Applied Spectroscopy·Toni Llorente-MirandesJosé Fermín López-Sánchez
Apr 15, 2017·Environmental Research·Shohreh F FarzanMargaret R Karagas
Jul 6, 2017·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Jacob K KresovichLifang Hou
Jun 10, 2020·Toxicological Sciences : an Official Journal of the Society of Toxicology·Kevin S HsuRichard I Enelow
Mar 13, 2018·BMJ Open Diabetes Research & Care·Roger ChafeLeigh Anne Newhook
Nov 9, 2016·Environmental Health : a Global Access Science Source·Shohreh F FarzanMargaret Karagas
Jul 29, 2020·Journal of Exposure Science & Environmental Epidemiology·Shohreh F FarzanCarrie V Breton
May 6, 2019·Reproductive Toxicology·Julia VarshavskyTracey J Woodruff
Mar 8, 2021·Toxicological Sciences : an Official Journal of the Society of Toxicology·Julia R VarshavskyTracey J Woodruff
May 4, 2021·Journal of Exposure Science & Environmental Epidemiology·Yoshira Ornelas Van HorneJill E Johnston
Jul 13, 2021·Reviews on Environmental Health·Christiana KarachaliouIoannis Kalavrouziotis
Jul 27, 2021·Ecotoxicology and Environmental Safety·Xin WangYuanyuan Li

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Related Feeds

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.