Blood pressure control in patients initiating antihypertensive therapy

The Annals of Pharmacotherapy
Derek WeyckerGerry Oster

Abstract

Although information concerning the attainment of goal blood pressure for patients commencing antihypertensive therapy is available from controlled trials, no studies have examined this issue in the context of typical clinical practice. To examine attainment of blood pressure control over time in patients initiating antihypertensive therapy in clinical practice. Using an electronic medical records database, we identified all adults with systolic blood pressure (SBP)/diastolic blood pressure (DBP) of 140/90 mm Hg or higher who initiated antihypertensive drug therapy. Subjects were stratified into subgroups based on the presence of high-risk conditions or characteristics described by the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure in their seventh report as "compelling indications" (eg, diabetes) or "special situations" (eg, obesity). Blood pressure control was examined in terms of goal attainment and reductions in blood pressure using last available readings at days 90, 180, and 360, following therapy initiation. Among the 10,345 study subjects, 47% had compelling indications and 39% had special situations. In the former group, 62% (95% CI 61 to 64) of patients with Sta...Continue Reading

References

Aug 18, 1999·Blood Pressure Monitoring·N R CampbellD W McKay
Oct 20, 2001·Hypertension·E L KnightJ Avorn
Nov 2, 2002·Hypertension·Donald M Lloyd-JonesDaniel Levy
Dec 6, 2003·Hypertension·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
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Dec 21, 2005·American Journal of Hypertension·Norm R C CampbellDonald W McKay
Dec 21, 2005·Medical Care·Michael L JohnsonRebecca J Beyth

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Citations

Apr 2, 2010·Cerebrovascular Diseases·Meng Lee, Bruce Ovbiagele
Jun 12, 2013·Current Medical Research and Opinion·Ishveen ChopraSean D Candrilli
Aug 13, 2011·American Heart Journal·James B ByrdP Michael Ho
Jan 26, 2011·Journal of Cardiovascular Disease Research·Manuel MorgadoMiguel Castelo-Branco
Jan 25, 2011·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Manuel P MorgadoMiguel Castelo-Branco

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