Blood pressure for outcome prediction and risk stratification in acute pulmonary embolism

The American Journal of Emergency Medicine
Karsten KellerWolfgang Dippold

Abstract

Risk stratification of patients with acute pulmonary embolism (PE) is crucial in deciding appropriate therapy management. Blood pressure (BP) is rapidly available and a reliable parameter. We aimed to investigate BP for short-term outcome in acute PE. Data of 182 patients with acute PE were analyzed retrospectively. Logistic regression models were calculated to investigate associations between BP and in-hospital-death as well as myocardial necrosis. Moreover, receiver operating characteristic (ROC) curves and cutoff values for systolic and diastolic BPs predicting in-hospital death and myocardial necrosis were computed. A total of 182 patients (61.5% female; mean age, 68.5 ± 15.3 years) with acute PE event were included in the study. Five patients (2.7%) died in the hospital. Logistic regression models showed a significant association between in-hospital death and systolic BP ≤ 120 mm Hg (odds ratio [OR], 22.222; 95% confidence interval [CI], 2.370-200.00; P = .00660), systolic BP ≤ 110 mm Hg (OR, 22.727; 95% CI, 3.378-142.857; P = .00130), systolic BP ≤ 100 mm Hg (OR, 16.129; 95% CI, 2.304-111.111; P = .00513), systolic BP ≤ 90 mm Hg (OR, 22.727; 95% CI, 3.086-166.667'; P = .00220), and diastolic BP ≤65 mm Hg (OR, 14.706; 95% ...Continue Reading

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Citations

Jun 20, 2020·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Jialong ChenSongjing Shi
Sep 1, 2017·Internal Medicine Journal·Anver SethwalaNadia D Friedman
Mar 6, 2021·Journal of Thrombosis and Thrombolysis·Mauricio Castillo-PerezMauricio Vazquez-Guajardo

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