Sep 1, 2007

Blood pressure in relation to the incidence of cerebral infarction and intracerebral hemorrhage. Hypertensive hemorrhage: debated nomenclature is still relevant

Stroke; a Journal of Cerebral Circulation
Elisabet ZiaGunnar Engström

Abstract

Data regarding the association between blood pressure level and incidence of stroke subtype, especially primary intracerebral hemorrhage (PICH) subtypes, is sparse. This population-based study explored the relationship between blood pressure and the incidence of cerebral infarction, and PICH, with lobar and nonlobar location. Risk factors were assessed in 27,702 men and women without prior stroke from the city of Malmö, Sweden. Mean age was 58.1 years. In all, 701 subjects had stroke (613 cerebral infarction and 88 PICH) during the follow-up period (mean, 7.5 years). The age- and sex-standardized incidences of cerebral infarction in subjects with hypertension grade 3 (>or=180/110 mm Hg) and normal blood pressure (<140/90 mm Hg) were 6.8 and 1.7 per 1000 person-years, respectively. Compared with the normotensive group, the adjusted relative risk of cerebral infarction was 3.4 (95% CI: 2.6 to 4.5) in subjects with hypertension grade 3. The corresponding incidences of lobar PICH were 0.5 versus 0.08 per 1000 person-years, respectively (adjusted relative risk: 9.2, 95% CI: 2.6 to 32.6) and for nonlobar PICH 1.6 versus 0.09 per 1000 person-years, respectively (adjusted relative risk: 25.9, 95% CI: 8.2 to 82.3). The incidence of hemo...Continue Reading

Mentioned in this Paper

Ischemic Cerebrovascular Accident
Diastolic Blood Pressure
Acute Cerebrovascular Accidents
Cerebrovascular Accident
Hypertensive Disease
Cerebral Hemorrhage
ERCC6L gene
Blood Pressure
Hemorrhage
Nomenclature

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