Blood pressure is not associated with haematoma enlargement in acute intracerebral haemorrhage

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
J Martí-FàbregasJ-L Martí-Vilalta

Abstract

We performed an observational study that compared baseline and subsequent blood pressure (BP) measurements and its association with haematoma enlargement (HE) in patients with intracerebral haemorrhage (ICH). We prospectively studied consecutive patients with supratentorial spontaneous ICH within the first 6 h after the onset of symptoms. HE was defined as an increase >or=33% in the volume of haematoma on the CT obtained 24-48 h after the onset of symptoms as compared with the CT at admission. We recorded systolic BP (SBP), diastolic BP (DBP) and mean BP (MBP) at admission and at 6, 12, 18 and 24 h after onset; the maximum SBP, DBP and MBP during the study period; the maximum SBP and DBP within intervals; the mean of all BP readings; administration of antihypertensive agents. We studied 60 patients whose mean age was 72.1 +/- 11.3 years. HE was observed in 27 (45%) patients. No statistically significant differences were observed in any of the analyses that compared BP parameters between the HE and non-HE groups (two-way anova). In an exploratory analysis, we did not find an association between BP and HE within the first 24 h after an acute ICH.

References

Jul 1, 1992·Neurosurgery·H G BaeI S Lee
Feb 1, 1990·Journal of Neurosurgery·J P BroderickJ Spilker
Nov 1, 1989·Neurology·S T ChenE L Hogan
Oct 1, 1996·Stroke; a Journal of Cerebral Circulation·S KazuiT Yamaguchi
Jan 1, 1997·Stroke; a Journal of Cerebral Circulation·T BrottJ Khoury
Dec 31, 1997·Stroke; a Journal of Cerebral Circulation·S KazuiT Yamaguchi
Jun 17, 1998·Stroke; a Journal of Cerebral Circulation·Y FujiiR Tanaka
Jan 4, 2003·Stroke; a Journal of Cerebral Circulation·Stephan A Mayer
Feb 20, 2004·Journal of Human Hypertension·A H G RasoolR B Singh
Aug 12, 2004·Neurology·R LeiraUNKNOWN Stroke Project, Cerebrovascular Diseases Group of the Spanish Neurological Society
Nov 20, 2004·Stroke; a Journal of Cerebral Circulation·Yolanda SilvaUNKNOWN Stroke Project, Cerebrovascular Diseases Group of the Spanish Neurological Society
Feb 25, 2005·The New England Journal of Medicine·Stephan A MayerUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
Apr 26, 2006·Neurology·S M DavisUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
Feb 10, 2007·Stroke; a Journal of Cerebral Circulation·Joseph P BroderickUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators

❮ Previous
Next ❯

Citations

Sep 30, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S Sacco, A Carolei
Feb 9, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S TetriM Hillbom
Dec 17, 2011·Lancet Neurology·Joyce S Balami, Alastair M Buchan
May 8, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D Rodriguez-LunaC A Molina
Dec 15, 2010·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Noriko MatsumotoJunya Aoki
Jan 14, 2010·Critical Care Medicine·Paul Nyquist
Dec 30, 2009·Current Opinion in Neurology·George NtaiosPatrik Michel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomegaly

Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.