Blood pressure variability estimated by ARV is a predictor of poor short-term outcomes in a prospective cohort of minor ischemic stroke

PloS One
Zefeng TanAnding Xu

Abstract

Prior studies have shown that patients with minor ischemic stroke have substantial disability rates at hospital discharge. We sought to determine whether blood pressure variability (BPV) estimated by average real variability (ARV) is one of the predictors of poor outcome at 90 days. Four hundred fifty-one consecutive patients with ischemic stroke treated within 7 days after onset were enrolled prospectively. Baseline magnetic resonance imaging (MRI) was performed on all subjects. Blood pressure was measured for all recruited patients every 2 hours in the first 24 hours after admission, followed by measurements collected every 4 hours from day 2 to day 7 after admission. ARV was used to estimate BPV. A total of 192 patients with minor ischemic stroke were enrolled, and 11 of them (5.7%) had poor outcomes. Univariate regression analysis showed that early neurological deterioration (X2 = 21.44, P = 0.000), severe symptomatic large artery stenosis or occlusion (X2 = 9.260, P = 0.000), large artery atherosclerotic stroke (X2 = 7.14, P = 0.002), total cholesterol (TC), and D2-7 SBP-ARV (t = 5.449, P = 0.001) of the poor outcome group were significantly higher than those of the good outcome group. Multivariate logistic regression anal...Continue Reading

References

Aug 1, 1978·Neurology·J P MohrH L Bleich
Aug 15, 1991·The New England Journal of Medicine·UNKNOWN North American Symptomatic Carotid Endarterectomy Trial CollaboratorsM Eliasziw
Apr 30, 1998·Archives of Neurology·H YamamotoG van Melle
Sep 23, 2003·Stroke; a Journal of Cerebral Circulation·Stella AslanyanUNKNOWN GAIN International Steering Committee and Investigators
Jan 17, 2004·Stroke; a Journal of Cerebral Circulation·José CastilloAntoni Dávalos
Feb 18, 2005·Journal of Hypertension·Luis MenaTulio Sulbarán
Oct 29, 2005·Stroke; a Journal of Cerebral Circulation·Mei YongJochen Mau
Sep 8, 2006·Journal of Hypertension·Nikolaos A ZakopoulosSpyridon D Moulopoulos
Oct 10, 2006·American Journal of Hypertension·Sante D PierdomenicoAndrea Mezzetti
Jan 31, 2007·American Journal of Hypertension·Paolo VerdecchiaGianpaolo Reboldi
Dec 22, 2007·Stroke; a Journal of Cerebral Circulation·Mei Yong, Markku Kaste
Apr 11, 2009·Stroke; a Journal of Cerebral Circulation·Gillian M SareUNKNOWN VISTA Collaboration
Jun 6, 2009·American Journal of Hypertension·Sante D PierdomenicoFranco Cuccurullo
Jan 13, 2010·Neurology·J FerrariUNKNOWN Austrian Stroke Unit Registry Collaborators
Feb 27, 2010·Stroke; a Journal of Cerebral Circulation·Urs FischerHeinrich P Mattle
Mar 10, 2010·Hypertension·Tine W HansenUNKNOWN International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes Investigators
Jul 8, 2010·Hypertension·Eamon Dolan, Eoin O'Brien
Mar 28, 1914·British Medical Journal·J A Macwilliam, G S Melvin
Jan 14, 2011·Diabetes Care·UNKNOWN American Diabetes Association
Mar 25, 2011·Journal of Hypertension·Efstathios ManiosNikolaos Zakopoulos
Jan 19, 2013·Stroke; a Journal of Cerebral Circulation·Kaoru EndoKazunori Toyoda
Jun 28, 2013·The New England Journal of Medicine·Yongjun WangUNKNOWN CHANCE Investigators
Dec 11, 2013·Hypertension·Giuseppe SchillaciBenjamin Gavish
Jun 8, 2014·Neurology·Shoichiro SatoUNKNOWN Stroke Unit Multicenter Observational (SUMO) Study Investigators
Aug 6, 2015·Stroke; a Journal of Cerebral Circulation·Lisa S ManningThompson G Robinson
Dec 10, 2015·BMC Neurology·Lingyun WuUNKNOWN China National Stroke Registry investigators

❮ Previous
Next ❯

Citations

Apr 17, 2020·Stroke; a Journal of Cerebral Circulation·Yasir SaleemDiogo C Haussen

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.