PMID: 2481533Jan 1, 1989Paper

[Blood replacement in heart transplantation].

Beiträge zur Infusionstherapie = Contributions to infusion therapy
L von SegesserM Turina

Abstract

Transfusion of blood and blood products in orthotopic heart transplantations were analysed in a series of 31 consecutive patients operated upon between September 1985 and December 1987. Mean age of the 29 men and 2 women was 41 +/- 12 years (range: 15-63). All patients had to be assigned to NYHA functional class IV before operation and their mean left ventricular fraction was 20%. The etiologies of cardiac disease leading to transplantation in this series were: cardiomyopathy in 19/31 patients (61%), ischemic heart disease in 7/31 (23%), valvular disease in 2/31 (6%), life threatening arrythmias in 2/31 (6%) and primary cardiac tumor in 1/31 (3%). Previous cardiac surgery had been performed in 6/31 patients (19%). Full anticoagulation with coumarines was observed in 24/31 patients (77%) at the time of surgery when mean PT was 33 +/- 12% and mean hematocrit was 40 +/- 4%. Mean blood products transfusion requirements in patients receiving an orthotopic heart transplant were 24.2 +/- 14.7 units (range 7-67 units) during the entire hospital stay. These figures are even higher if compiled in function of the number of donors of the transfused blood products: 29.2 +/- 22.4 (range 7-105). The following mean number of blood and blood co...Continue Reading

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