Blood rheology in PCA and PCEA after total knee arthroplasty

The Journal of Arthroplasty
Benzion BeilinHanna Bessler

Abstract

The rheological events in 2 groups of patients undergoing total knee arthroplasty were compared--15 patients were given general anesthesia and controlled their postoperative pain applying intravenous patient-controlled analgesia; 17 individuals received combined spinal-epidural anesthesia and controlled their postoperative pain by patient-controlled epidural analgesia (PCEA). Twenty-four and 48 hours after surgery, the patient-controlled analgesia group showed a significant increase in whole-blood viscosity at the 3 shear rates (P < .01), as well as in relative viscosity at both periods (P < .001 and .01, respectively). Similar findings were observed for red blood cell aggregation (P < .001) and fibrinogen level (P < .001). These values were less expressed in the PCEA group, particularly 48 hours after surgery (P < .01), and the patients showed lower scores on the visual analog pain scale. The better results observed in the PCEA group favor the application of epidural anesthesia and PCEA analgesia in patients undergoing total knee arthroplasty.

References

Jun 1, 1992·Anesthesia and Analgesia·J A OdoomW W Zuurmond
Jan 1, 1991·British Journal of Anaesthesia·L N JørgensenE Albrecht-Beste
May 1, 1993·Journal of Clinical Anesthesia·J C BallantyneF Mosteller
Aug 10, 2000·Anesthesiology Clinics of North America·J A Grass
Apr 7, 2004·The Journal of Arthroplasty·Christopher BrowneClifford Colwell

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Citations

Jun 26, 2007·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Dusica M StamenkovićVitomir I Ranković
Oct 26, 2007·Brain, Behavior, and Immunity·Irit Shapira-LichterRaz Yirmiya

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