PMID: 18711984Aug 21, 2008Paper

Blood safety & prevalence of transfussion transmissible viral infections among donors at the Red Cross Blood Bank in Gondar University Hospital

Ethiopian Medical Journal
Ermias DiroAsfawesen G/Yohannes

Abstract

Although millions of lives are saved by blood transfusion, unsafe transfusion is also putting millions of people at risk of Transfusion Transmissible Infections (TTI). In Ethiopia the safety and magnitude of blood transfusion and TTIs is not well investigated to investigate the magnitude of TTIs and assess TTI related risk factors among blood donors. Cross-sectional study among blood donors at the Red Cross Society Blood Bank in Gondar University Hospital, North West Ethiopia. The study was conducted among 600 adult blood donors between April and July 2004. Their mean age was 28 +/- 10.4 years (range: 16-64) and 66% of them were urban dwellers. The donors included farmers (30.7%), daily laborers (22.7%) and students (20%). All the donors were first time donors and 75% of the donations were replacement donations by remunerated donors or family members. The prevalence of HIV, Hepatitis B surface antigen (HBSAg) and Hepatitis C virus (HCV) infections were 4.5% (95%CI: 3.0-6.6), 8.2% (95%CI: 6.2-10.7) and 5.8% (95%CI: 4.2-8.1), respectively. The overall discard rate of donated blood because of these viral markers was 16.3%. In univariate analysis, HCV infection was significantly associated with presence of HIV (OR: 5.36, 95%CI: 2-1...Continue Reading

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