Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery

Annals of Cardiac Anaesthesia
Bharathi H ScottRoger Grimson

Abstract

The purpose of the present investigation was to examine the impact of blood transfusion on resource utilisation, morbidity and mortality in patients undergoing coronary artery bypass graft (CABG) surgery at a major university hospital. The resources we examined are time to extubation, intensive care unit length of stay (ICULOS) and postoperative length of stay (PLOS). We further examined the impact of number of units of packed red blood cells (PRBCs) transfused during PLOS. This is a retrospective observational study and includes 1746 consecutive male and female patients undergoing primary CABG (on- and off-pump) at our institution. Of these, 1067 patients received blood transfusions, while 677 did not. The data regarding the demography, blood transfusion, resource utilisation, morbidity and mortality were collected from the records of patients undergoing CABG over a period of three years. The mean time to extubation following surgery was 8.0 h for the transfused group and 4.3 h for the nontransfused group ( P <or= 0.001). The mean ICULOS for the transfused group was 1.6 d and 1.2 d for the nontransfused group ( P P <or= 0.001). In all patients and in patients with no preoperative morbidity, partial correlation coefficients wer...Continue Reading

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Citations

Aug 20, 2010·Intensive Care Medicine·Patrick MöhnleUNKNOWN Multicenter Study of Perioperative Ischemia (McSPI) Research Group
May 24, 2013·Journal of Anesthesia·Tomonori MatsuyamaKohei Kawashima
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