Blood Transfusion Strategies for Hemostatic Resuscitation in Massive Trauma

The Nursing Clinics of North America
Caroline McGrath

Abstract

Massive transfusion practices were transformed during the 1970s without solid evidence supporting the use of component therapy. A manual literature search was performed for all references to the lethal triad, acute or early coagulopathy of trauma, fresh whole blood, and component transfusion therapy in massive trauma, and damage control resuscitation. Data from recent wars suggest traditional component therapy causes a nonhemostatic resuscitation worsening the propagation of the lethal triad hastening death. These same studies also indicate the advantage of fresh whole blood over component therapy even when administered in a 1:1:1 replacement ratio.

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Citations

Jul 10, 2019·Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses·Nicole R DiFrancescoKirsten A Hickerson
Mar 12, 2020·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Fan ZhangJin Liu
Aug 29, 2020·The American Journal of Nursing·Nicole W CaldwellChristopher A VanFosson
Feb 20, 2020·Revista latino-americana de enfermagem·Maicon Henrique LentsckThais Aidar de Freitas Mathias
Sep 16, 2020·Internal and Emergency Medicine·Mario CrucianiGiancarlo Maria Liumbruno

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