Blood vessels of the Peyer's patch in the mouse: II. In vivo observations

The Anatomical Record
K Yamaguchi, G I Schoefl

Abstract

A technique was developed that allowed the in vivo observation of Peyer's patches in the mouse for several hours. Untreated animals and animals depleted of lymphocytes were used. In this species, blood vessels associated with the lymphoid nodules are readily visible through the thin serosal muscle coat. High-endothelium venules are recognized by the large number of refractile cells that adhere to the luminal surface. A colloidal carbon suspension injected intravenously labeled high-endothelium venules and was only rarely seen in arterial and capillary segments or in venules of the gut parenchyma. When fluorescein isothiocyanate-labeled (FITC-labeled) syngeneic spleen cells were injected, they appeared in vessels of the Peyer's patch within a few seconds and began to adhere to the luminal surface of high-endothelium venules. In untreated animals, peak numbers of fluorescent cells were reached after about 20 min. Many adhered but some were swept away. In lymphocyte-depleted animals, however, peak numbers were reached after only a few minutes and most cells remained attached.

References

Jan 1, 1979·Advances in Experimental Medicine and Biology·M E Smith, W L Ford
Oct 1, 1975·Cellular Immunology·W van EwijkJ Rozing
May 1, 1975·The American Journal of Anatomy·A G Farr, P P De Bruyn
May 1, 1974·Journal of Ultrastructure Research·E J WenkJ A Rhodin
Dec 1, 1967·Scandinavian Journal of Haematology·N Söderström
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·C RöpkeM H Claësson
Jun 1, 1971·Experimental and Molecular Pathology·A Mikata, R Niki
Jan 1, 1968·The Journal of Experimental Medicine·I Goldschneider, D D McGregor
Aug 1, 1983·The Anatomical Record·K Yamaguchi, G I Schoefl
Aug 1, 1983·The Anatomical Record·K Yamaguchi, G I Schoefl
Jan 1, 1980·Ciba Foundation Symposium·P AndrewsR W Stoddart
Jan 1, 1980·Ciba Foundation Symposium·J J Woodruff, B J Kuttner
Jan 1, 1980·Journal of Immunological Methods·E C Butcher, I L Weissman
Jul 1, 1960·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·W E STEHBENS, H W FLOREY
Jan 14, 1964·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·J L GOWANS, E J KNIGHT
Jan 14, 1964·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·V T MARCHESI, J L GOWANS
Apr 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·E E HANNA, D W WATSON
Dec 1, 1961·The Journal of Biophysical and Biochemical Cytology·G MAJNOG I SCHOEFL

❮ Previous
Next ❯

Citations

Oct 7, 2003·Archives of Histology and Cytology·Osamu OhtaniBren J Gannon
Aug 1, 1983·The Anatomical Record·K Yamaguchi, G I Schoefl
Aug 1, 1983·The Anatomical Record·K Yamaguchi, G I Schoefl

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.