Blue emitting nitrogen-doped carbon dots as a fluorescent probe for nitrite ion sensing and cell-imaging

Analytica Chimica Acta
Jayasmita JanaSeung Hyun Hur

Abstract

This study examined the efficiency of pH-dependent, fluorescent carbon dots for the sensing of hazardous anions in aqueous media and cell imaging. The nitrite anion, an important water-soluble element for environmental and biological systems, requires continuous monitoring because a high concentration can affect the systems severely. The as-synthesized carbon dots efficiently detected the nitrite anion in aqueous solution through a fluorescent 'Turn Off' phenomenon. The quenching mechanism was investigated through proper microscopic and spectroscopic studies. The limit of detection and linear detection range were 7.9 nM and 2.3μM-7.7 mM, respectively. The sensitivity was tested with different water samples. In a parallel experiment, the as-synthesized carbon dots were used as a cell-imaging probe for HeLa cells, highlighting their potential in different biological studies.

Citations

Feb 20, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jing JiaShaomin Shuang
Mar 19, 2020·Photochemistry and Photobiology·Fatemeh HashemiNosratollah Zarghami
Nov 27, 2020·Nanomaterials·Chao KangZeng Ping Chen
Jan 20, 2021·Analytica Chimica Acta·Mengli YangDai-Wen Pang
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Tengfei WangYu Wang
Jul 29, 2021·Analytical Methods : Advancing Methods and Applications·Yafeng DengJun Qian
Jul 31, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Guili GeCan Guo
Oct 31, 2021·Cell Biochemistry and Biophysics·Fatemeh HeidariNosratollah Zarghami

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