Blue-yellow and standard pattern visual evoked potentials in phakic and pseudophakic glaucoma patients and controls

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Matthias FuestNiklas Plange

Abstract

Blue-yellow short wavelength testing (BY-VEPs) has proven diagnostic relevance in detecting early ganglion cell damage, e.g., in glaucoma. To date testing has generally been conducted using individual protocols without consideration of the lens status. In this study, we compared changes in BY-VEPs and standard pattern VEPs in phakic and pseudophakic glaucoma patients and controls. The eyes of 57 healthy controls (18 pseudophakic and 39 phakic) and 67 glaucoma patients (29 pseudophakic and 38 phakic) were included in a prospective study. Phakic eyes were arranged in three groups according to the Lens Opacities Classification System III. Transient on/off isoluminant blue-yellow 2° checks were used for BY-VEPs, transient large 1° (M1) and small 0.25° (M2) black-white checks for standard pattern reversal VEPs, according to the ISCEV standards. Latencies and amplitudes of M1 and M2 did not differ significantly between groups or lens status. ANOVA analysis revealed significantly longer BY-VEP latencies in glaucoma compared to controls (p = 0.002), independently of the lens status. The amplitudes showed no such pattern (p = 0.93). Mean defect (MD) was significantly negatively correlated to BY-VEP latency (r = -0.54, p = 0.003) only in...Continue Reading

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Citations

Jul 28, 2018·Translational Vision Science & Technology·Duoru LinYizhi Liu
Jun 13, 2021·Eye·Oliver R Marmoy, Suresh Viswanathan
Nov 26, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Laura Dussan MolinosFolkert K Horn

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