Blurring the Lines between Host and Guest: A Chimeric Receptor Derived from Cucurbituril and Triptycene

Angewandte Chemie
Xiaoyong LuLyle Isaacs

Abstract

We report the synthesis and X-ray crystal structure of a cucurbituril-triptycene chimeric receptor (1). Host 1 binds to guests typical of CB[6]-CB[8], but also binds to larger guests such as blue box (20) and the Fujita square (22). Intriguingly, the geometries of the 1⋅20 and 1⋅22 complexes blur the lines between host and guest in that both components fulfill both roles within each complex. The fluorescence output of 1 is fully quenched by the formation of complexes with pyridinium-derived guests.

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Citations

May 22, 2019·Organic & Biomolecular Chemistry·Weijian XueLyle Isaacs
Jul 28, 2019·Chemistry : a European Journal·Michael Heilmann, Konrad Tiefenbacher
Aug 30, 2018·Organic & Biomolecular Chemistry·Wenjin LiuLyle Isaacs
Aug 21, 2019·Chemical Communications : Chem Comm·Wenjin LiuQiaoli Yan
Oct 13, 2020·Chemical Society Reviews·Chun-Lin DengLyle D Isaacs
Jan 14, 2021·Chemical Communications : Chem Comm·Yufeng HuoZhanhu Guo
Nov 4, 2020·Journal of Computer-aided Molecular Design·Yuanjun ShiJay W Ponder
Jan 1, 2020·New Journal of Chemistry = Nouveau Journal De Chimie·Sandra Zebaze NdendjioLyle Isaacs
Mar 1, 2019·Journal of the American Chemical Society·Tomoyuki IkaiTimothy M Swager
Jan 7, 2022·The Journal of Physical Chemistry Letters·Kaiyuan HuangHaohua Deng

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