BMI > or = 50 kg/m2 is associated with a younger age of onset of overweight and a high prevalence of adverse metabolic profiles

Public Health Nutrition
Jean O'ConnellDonal O'Shea

Abstract

To study the demographic and clinical parameters of three different categories of obesity, with particular focus on a cohort of individuals with BMI > or = 50 kg/m2, the fastest growing category of obesity. Over 700 obese individuals were studied (186 with BMI = 30-39 kg/m2, 316 with BMI = 40-49 kg/m2 and 290 with BMI > or = 50 kg/m2). Median BMI was 51 kg/m2 for patients who reported onset of overweight before 15 years of age, 47 kg/m2 for patients who reported onset between 15 and 30 years, and 42 kg/m2 for patients who became overweight after 30 years of age. The BMI > or = 50 kg/m2 group was notably younger than the group with BMI = 30-39 kg/m2 (44 (SD 11) years v. 50 (SD 15) years; P < 0.0001). Eighteen per cent of obese patients studied were considered metabolically healthy according to standard cut-off points for blood pressure, fasting glucose and lipid profiles. However, the proportion of metabolically healthy individuals was significantly higher in the BMI = 30-39 kg/m2 group than in the BMI = 40-49 kg/m2 and BMI > or = 50 kg/m2 groups (31% v. 17% and 12% respectively; P < 0.05 and P < 0.005). When compared with people of similar age in the general population, individuals with BMI > or = 50 kg/m2 had lower rates of ma...Continue Reading

References

Jul 1, 1992·The American Journal of Clinical Nutrition·V A CaseyI Valadian
Apr 1, 1994·The American Journal of Clinical Nutrition·S S GuoR M Siervogel
Mar 1, 1993·Preventive Medicine·M K SerdulaT Byers
Apr 16, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E MuscelliE Ferrannini
Dec 6, 2001·Metabolism: Clinical and Experimental·E A Sims
Mar 21, 2003·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Kenneth F FerraroJody A Wilkinson
Nov 19, 2003·Annals of Internal Medicine·Tracey McLaughlinGerald Reaven
Apr 28, 2005·The Journal of Clinical Endocrinology and Metabolism·Antony D KarelisRemi Rabasa-Lhoret
Jun 25, 2005·Obesity Research·Gianluca IacobellisFrida Leonetti
Sep 29, 2005·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·C Lundh HagelinC J Fürst
Apr 3, 2007·Public Health·R Sturm
May 15, 2007·Gastroenterology·Cynthia L OgdenKatherine M Flegal
Aug 13, 2008·Archives of Internal Medicine·Norbert StefanHans-Ulrich Häring
Jul 11, 2009·Journal of Pediatric Gastroenterology and Nutrition·Wieland KiessAntje Körner

❮ Previous
Next ❯

Citations

Oct 11, 2019·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Jessica G WooAlison Venn
May 17, 2015·The Journal of Immunology : Official Journal of the American Association of Immunologists·Eirin CarolanAndrew E Hogan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved