Bmp4 and morphological variation of beaks in Darwin's finches

Science
Arhat AbzhanovClifford J Tabin

Abstract

Darwin's finches are a classic example of species diversification by natural selection. Their impressive variation in beak morphology is associated with the exploitation of a variety of ecological niches, but its developmental basis is unknown. We performed a comparative analysis of expression patterns of various growth factors in species comprising the genus Geospiza. We found that expression of Bmp4 in the mesenchyme of the upper beaks strongly correlated with deep and broad beak morphology. When misexpressed in chicken embryos, Bmp4 caused morphological transformations paralleling the beak morphology of the large ground finch G. magnirostris.

References

Apr 15, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·I SembaH C Slavkin
Dec 5, 2002·Mechanisms of Development·Sabine OhnemusMoisés Mallo
Jan 25, 2003·Science·R A Schneider, J A Helms
Dec 31, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Paul KulesaPaul A Trainor
Sep 9, 2004·Science·Ping WuCheng-Ming Chuong

❮ Previous
Next ❯

Citations

Feb 12, 2013·Hearing Research·Ulrike J Sienknecht
Oct 15, 2013·Trends in Genetics : TIG·Arhat Abzhanov
Jan 23, 2013·Trends in Ecology & Evolution·Duncan J IrschickElizabeth Dumont
Oct 2, 2008·The Behavioral and Brain Sciences·Morten H Christiansen, Nick Chater
Sep 19, 2008·Nature·John Whitfield
Sep 11, 2008·Heredity·A Qvarnström, R I Bailey
Feb 25, 2010·Nature Reviews. Neuroscience·Reha S ErzurumluFilippo M Rijli
Aug 12, 2005·Heredity·S B Piertney, M K Oliver
Jul 13, 2006·Heredity·R C Albertson, T D Kocher
Jul 13, 2006·Heredity·D M Parichy
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Chris R FeldmanMichael E Pfrender
May 22, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kaspar Mossman
Sep 2, 2009·Proceedings of the National Academy of Sciences of the United States of America·Sophie E Creuzet
Feb 18, 2010·Proceedings of the National Academy of Sciences of the United States of America·O CampàsM P Brenner
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jonathan B SylvesterJ Todd Streelman
Mar 27, 2010·Proceedings of the National Academy of Sciences of the United States of America·Farooq Ahmed
Mar 4, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ricardo MallarinoArhat Abzhanov
Jul 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Reade B RobertsThomas D Kocher
Jun 22, 2011·Proceedings of the National Academy of Sciences of the United States of America·Prashant Nair
Jul 17, 2012·Proceedings of the National Academy of Sciences of the United States of America·Rebecca C IskowCharles Lee
Jan 19, 2010·Briefings in Functional Genomics·Katja Nowick, Lisa Stubbs
Aug 9, 2011·Human Molecular Genetics·Eva Lana-ElolaDavid P Rice
Oct 1, 2008·Integrative and Comparative Biology·Christopher J Schneider
Mar 26, 2010·Journal of Experimental Botany·Ruth C MartinHiroyuki Nonogaki
Jan 29, 2013·Molecular Biology and Evolution·Maxim V KapralovDmitry A Filatov
Sep 30, 2005·Proceedings. Biological Sciences·Martin Wikelski
Jun 5, 2010·Proceedings. Biological Sciences·Chris R FeldmanMichael E Pfrender
May 30, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·B Rosemary Grant, Peter R Grant
Dec 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Graham Bell
Mar 3, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Joris SoonsJoris Dirckx
Mar 3, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Alexander V Badyaev
Mar 3, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Luis Fernando de LeónAndrew P Hendry
Mar 3, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Arhat Abzhanov
Jul 21, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Josephine M Pemberton
Nov 17, 2010·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Alison M Bell, Nadia Aubin-Horth
Jun 22, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Rinaldo C Bertossa
May 8, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Alvaro Rada-IglesiasJoanna Wysocka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Developmental Dynamics : an Official Publication of the American Association of Anatomists
Ping WuCheng-Ming Chuong
Proceedings of the National Academy of Sciences of the United States of America
R Craig AlbertsonPamela C Yelick
© 2021 Meta ULC. All rights reserved