Body Composition and Diabetes Risk in South Asians: Findings From the MASALA and MESA Studies.

Diabetes Care
Elena FlowersAlka Kanaya

Abstract

South Asians have a higher prevalence of type 2 diabetes compared with other race/ethnic groups. Body composition is associated with the risk for type 2 diabetes. Differences in body composition between South Asians and other race/ethnic groups are one hypothesized mechanism to explain the disproportionate prevalence of type 2 diabetes in this population. This study used data from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and the Multi-Ethnic Study of Atherosclerosis (MESA) cohorts to determine whether body composition mediated the elevated prevalence of impaired fasting glucose and type 2 diabetes in South Asians. Participants (n = 2,615) with complete body composition data were included. Ordinal logistic regression models were calculated to determine the odds for glycemic impairment in South Asians compared with the MESA cohort. In multivariate models, South Asians had a significantly higher prevalence of glycemic impairment and type 2 diabetes compared with all four race/ethnic groups included in the MESA (P < 0.001 for all). In unadjusted and multivariate adjusted models, South Asians had higher odds for impaired fasting glucose and type 2 diabetes compared with all other race/ethnic groups...Continue Reading

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Citations

Jul 16, 2020·Pediatric Diabetes·Risa M WolfSheela N Magge
Oct 13, 2019·Cardiovascular Diabetology·Elisabeth H M PaimanHildo J Lamb
Nov 21, 2020·Annals of the New York Academy of Sciences·Unjali P Gujral, Alka M Kanaya
Feb 23, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Meghana D GadgilDavid M Herrington
Aug 7, 2021·Diabetes & Metabolism Journal·Iva MiljkovicMatthew Allison
Dec 11, 2021·Current Opinion in Endocrinology, Diabetes, and Obesity·Priyanka Bakhtiani, Mitchell E Geffner

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