Body composition reference charts for UK infants and children aged 6 weeks to 5 years based on measurement of total body water by isotope dilution.

European Journal of Clinical Nutrition
Jonathan C K WellsT J Cole

Abstract

Until recently, pediatric body composition reference data were very limited, hindering interpretation of measurements. In the last decade, such data emerged for several techniques for children ≥ 5 years, but equivalent data for younger age groups remain lacking, due to their poor compliance with most techniques. To provide reference data for use in clinical practice and research from 6 weeks to 5 years, that are based on measurements of total body water (TBW) by isotope dilution. The data on anthropometry and TBW were available from studies of 463 infants and children aged 6 weeks to 7 years, conducted between 1988 and 2010. Both breast-fed and formula-fed infants were included. TBW was measured by 2H- or 18O-labeled water, and converted to fat-free mass (FFM) using published hydration coefficients. Reference charts and SD scores (SDS) were constructed for FFM, fat mass (FM), FFM index and FM index for each sex, using the lambda-mu-sigma method. Both sexes were significantly heavier and longer than UK 1990 reference data (p < 0.01), but did not differ in body mass index SDS. Breast-fed infants were longer than formula-fed infants but did not differ in body composition. These reference data will enhance the ability of clinicians...Continue Reading

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Citations

May 30, 2020·The American Journal of Clinical Nutrition·Roman J Shypailo, William W Wong
Aug 7, 2020·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Estela Beatriz BehlingJacqueline Pontes Monteiro
Sep 9, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Hongbo DongUNKNOWN China Child and Adolescent Cardiovascular Health (CCACH) collaboration members
Jan 4, 2022·European Journal of Nutrition·Alexandra JungertUNKNOWN German Nutrition Society (DGE)

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