PMID: 8580616Nov 1, 1995Paper

Body growth in children with polycystic kidney disease. Arbeitsgemeinschaft für Pädiatrische Nephrologie

Acta Paediatrica
M KonradK Schärer

Abstract

We analysed the body growth of 121 prepubertal children with polycystic kidney disease participating in a longitudinal multicentre study. The patients were followed from an age of 1 to 9 years in girls and 1 to 10 years in boys over a mean period of 3.6 years. Children with end-stage renal disease were excluded. Fifty-four patients had the autosomal dominant form of the disease and 67 the autosomal recessive form. At last observation, 2% of patients with the dominant form and 28% of those with the recessive form had an estimated glomerular filtration rate of < 60 ml/(min 1.73 m2). At first observation, the mean height SD score (SDS) in patients with the dominant form was almost the same as in controls, whilst in those with the recessive form it was significantly decreased (girls -0.82 SDS, boys -0.68 SDS, p < 0.001). During the follow-up the height SDS decreased slightly in both groups (NS). In patients with autosomal recessive kidney disease the degree of growth retardation appeared to be related to renal function: at last observation the height of girls with an estimated glomerular filtration rate of < 60 ml/(min 1.73 m2) was more retarded than that of boys (mean -2.1 SDS versus -1.5 SDS, NS). The height SDS and renal functio...Continue Reading

References

May 1, 1977·The Journal of Pediatrics·B S KaplanK N Drummond
Jul 1, 1975·American Journal of Diseases of Children·S K AnandE Lieberman
Sep 1, 1992·The Clinical Investigator·K Zerres
Feb 1, 1991·Journal of Hypertension·S A de ManA Hofman
Dec 1, 1989·The Journal of Pediatrics·B S KaplanD S Rosenblatt
Jan 1, 1989·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·B S KaplanT M Barratt
Jul 1, 1988·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·H KääriäinenR Norio
Nov 1, 1987·The Journal of Pediatrics·B R ColeF B Stapleton
Aug 1, 1983·Kidney International·W C ArnoldM A Holliday
May 1, 1994·Acta Paediatrica·F SchaeferH J Bremer
Dec 1, 1993·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M BroyerK Schärer
Apr 1, 1993·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·C SeidelK Schärer

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