Body height and blood pressure regulation in humans during anti-orthostatic tilting

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Sine K ArvedsenP Norsk

Abstract

The hypothesis was tested that the cardiovascular changes during an upper body anti-orthostatic maneuver in humans are more pronounced in tall than in short individuals, because of the larger intravascular hydrostatic pressure gradients. In 34 males and 41 females [20-30 yr, body height (BH) = 147-206 cm], inter-individual multiple linear regression analyses adjusted for gender and body weight were conducted between changes in cardiovascular variables versus BH during tilting of the upper body from vertical to horizontal while keeping the legs horizontal. In all the subjects, tilting induced increases in stroke volume and arterial pulse pressure and a decrease in heart rate, which each correlated significantly with BH. In males (n = 51, BH = 163-206 cm), 24-h ambulatory mean arterial pressure increased significantly with BH (P = 0.004, r = 0.40, α = 0.15 mmHg/cm) so that systolic/diastolic blood pressure increased by 2/2 mmHg per 15 cm increase in BH. There was no significant correlation between mean arterial pressure and BH in females (n = 53, BH = 147-193 cm). In conclusion, a larger BH induces larger cardiovascular changes during anti-orthostatic tilting, and in males 24-h ambulatory mean arterial pressure increases with BH....Continue Reading

References

Jun 1, 1985·Journal of Applied Physiology·M C KallayC R Ortiz
Jan 1, 1974·American Journal of Epidemiology·H Kesteloot, O Van Houte
May 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·S MatalonL E Farhi
Jun 1, 1982·American Journal of Epidemiology·A W VoorsG S Berenson
Jul 1, 1993·European Journal of Pediatrics·F KrullJ Brodehl
Aug 5, 2000·Journal of Applied Physiology·D E WatenpaughP Norsk
Feb 13, 2001·American Journal of Physiology. Heart and Circulatory Physiology·P Van De BorneV K Somers
Jun 26, 2001·Acta Physiologica Scandinavica·B PumpP Norsk
Aug 22, 2001·American Journal of Physiology. Heart and Circulatory Physiology·B PumpP Norsk
Oct 22, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Morten DamgaardPeter Norsk
Mar 18, 2003·Journal of Hypertension·Claudia LangenbergMichael E Wadsworth
Sep 1, 1960·Circulation Research·R H GOETZM McGREGOR
May 13, 2005·Clinical Physiology and Functional Imaging·Morten Damgaard, Peter Norsk
Aug 7, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·E BrøndumT Wang

❮ Previous
Next ❯

Citations

Oct 25, 2013·Evolution; International Journal of Organic Evolution·Craig R White, Roger S Seymour
Jul 12, 2014·Journal of Physical Therapy Science·Jun MurataShohzo Matsubara
Feb 3, 2018·Medicine·Brianna BourgeoisSteven B Heymsfield
Aug 30, 2017·Frontiers in Physiology·Joyce M EvansDavid C Randall
Aug 21, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Sine Kongsbak ArvedsenMorten Damgaard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved