Body mass index, abdominal fatness, weight gain and the risk of urinary incontinence: a systematic review and dose-response meta-analysis of prospective studies

BJOG : an International Journal of Obstetrics and Gynaecology
Dagfinn AuneElio Riboli

Abstract

Adiposity has been associated with elevated risk of urinary incontinence in epidemiological studies; however, the strength of the association has differed between studies. To conduct a systematic literature review and dose-response meta-analysis of prospective studies on adiposity and risk of urinary incontinence. We searched PubMed and Embase databases up to 19 July 2017. Prospective cohort studies were included. Data were extracted by one reviewer and checked for accuracy by a second reviewer. Summary relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects models. Twenty-four prospective studies were included. The summary RR per 5 kg/m2 increment in body mass index (BMI) was 1.20 (95% CI 1.16-1.25, I2  = 62%, n = 11) for population-based studies and 1.19 (95% CI 1.08-1.30, I2  = 87.1%, n = 8) for pregnancy-based studies, 1.18 (95% CI 1.14-1.22, I2  = 0%, n = 2) per 10 cm increase in waist circumference and 1.34 (95% CI 1.11-1.62, I2  = 90%, n = 2) per 10 kg of weight gain. Although the test for nonlinearity was significant for BMI, P = 0.04, the association was approximately linear. For subtypes of urinary incontinence the summary RR per 5 BMI units was 1.45 (95% CI 1.25-1.68, I2  = 85%, n...Continue Reading

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Citations

Aug 23, 2020·Current Urology Reports·Amanda R Swanton, E Ann Gormley
Jul 7, 2020·Post Reproductive Health·Gemma Nightingale
Aug 9, 2020·Journal of Women's Health·Kil-Yong LeeKyungdo Han
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Feb 18, 2020·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Marit L Bovbjerg, Veronica Irvin
Apr 9, 2021·Obstetrics and Gynecology·Ingrid E NygaardJanet M Shaw
Mar 18, 2021·American Journal of Obstetrics and Gynecology·Mohammad AbufarajLin Yang
May 15, 2021·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Qingling ShiDan Liu

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