Body mass index and quality of bowel preparation: Real life vs. clinical trials

Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology
Ala I ShararaRobert H Habib

Abstract

Obesity is a recognised risk factor for poor bowel preparation in retrospective studies whilst corresponding data in prospective trials are marginally reported. Aims are to evaluate the relation between body mass index (BMI) and preparation quality in retrospective and interventional prospective settings and within a single centre. Data from a recent colorectal cancer screening registry were retrospectively analysed for the relation between BMI and adequacy of preparation. Patients were categorised as underweight (BMI<20kg/m(2)), normal (20-25kg/m(2)), overweight (25-30kg/m(2)), and obese (>30kg/m(2)). Data from a recent prospective colon preparation trial were similarly analysed. 541 registry patients were included. Multivariate analysis showed BMI to be an independent risk factor for inadequate preparation. Obesity was associated with odds ratio (OR) of 5.3 [95% confidence interval (CI) 1.4-19.8; p=0.01] compared to normal BMI. A significant difference was also noted in underweight but otherwise healthy individuals (OR=11.1, 95% CI 2-60; p=0.005). In the prospective study of 195 patients, obese patients had comparable rates of inadequate preparation to normal-weight individuals (OR=0.7, 95% CI 1.1-3.96; p=0.68). Underweight p...Continue Reading

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Citations

Jan 6, 2017·Clinical and Translational Gastroenterology·Ala I ShararaFayez S Sarkis
Dec 24, 2018·United European Gastroenterology Journal·Jarek KobielaMichał F Kamiński
Mar 7, 2021·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Ribwar A Mohammed, Samir Y Lafi

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