Body Mass Index and Stump Morphology Predict an Increased Incidence of Pancreatic Fistula After Pancreaticoduodenectomy

World Journal of Surgery
Chi-Hua FangWen Zhu

Abstract

A majority of factors associated with the occurrence of clinical relevant postoperative pancreatic fistula (CR-POPF) after pancreaticoduodenectomy (PD) can only be identified intra- or postoperatively. There are no reports for assessing the morphological features of pancreatic stump and analyzing its influence on CR-POPF risk after PD preoperatively. A total of 90 patients underwent PD between April 2012 and May 2014 in our hospital were included. Preoperative computed tomographic (CT) images were imported into the Medical Image Three-Dimensional Visualization System (MI-3DVS) for acquiring the morphological features of pancreatic stump. The demographics, laboratory test and morphological features of pancreatic stump were recorded prospectively. The clinical course was evaluated focusing on the occurrence of pancreatic fistula as defined by the International Study Group on Pancreatic Fistula (ISGPF). Logistic regression analysis was used to identify independent predictors of CR-POPF. CR-POPF occurred in 18 patients (14 grade B, 4 grade C). In univariate analysis, male gender (P = 0.026), body mass index (BMI) ≥ 25.3 kg/m(2) (P = 0.002), main pancreas duct diameter (MPDD) < 3.1 mm (P = 0.005), remnant pancreatic parenchymal volu...Continue Reading

References

Oct 31, 2001·The British Journal of Surgery·C GouillatB Gayet
Apr 16, 2005·World Journal of Gastroenterology : WJG·Yin-Mo YangYan-Ting Huang
Jul 9, 2005·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Fistula Definition
May 17, 2006·Surgery·Fabrice MuscariUNKNOWN French Associations for Surgical Research
Jun 24, 2006·Annals of Surgery·John L CameronKenneth A Belcher
Aug 2, 2007·The Journal of Craniofacial Surgery·Mehmet Emin MaviliIlken Kocadereli
Nov 29, 2007·Annals of Surgery·Abhishek MathurKeith D Lillemoe
Jan 5, 2008·World Journal of Surgery·Wande B PrattCharles M Vollmer
Dec 6, 2008·World Journal of Gastroenterology : WJG·Yun-Mee ChoeKyung-Rae Kim
Jul 30, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Edoardo RossoPhilippe Bachellier
Oct 21, 2010·The British Journal of Surgery·M KandaA Nakao
Jun 16, 2011·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Thilo HackertMarkus W Büchler
Sep 29, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yasushi HashimotoMichael B Farnell
May 23, 2012·International Journal of Surgical Oncology·Norman Oneil Machado
Aug 18, 2012·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Chi-hua FangShi zheng Zhong
Nov 6, 2012·Journal of the American College of Surgeons·Mark P CalleryCharles M Vollmer
Aug 2, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jordan M CloydJeffrey A Norton
May 28, 2014·Journal of the American College of Surgeons·Amber L SimpsonJames D Stefansic
Sep 19, 2014·World Journal of Gastrointestinal Oncology·Anna PalliseraJose Manuel Ramia
Dec 3, 2014·Journal of the American College of Surgeons·Chi-hua FangYing-fang Fan

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Citations

Jan 24, 2018·World Journal of Gastrointestinal Surgery·Narongsak RungsakulkijSuraida Aeesoa
Sep 21, 2018·Molecular and Clinical Oncology·Yusuke KumamotoMasahiko Watanabe
Jul 6, 2017·Nutrition Journal·Théophile GuilbaudVincent Moutardier
Nov 28, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ozgur AkgulTimothy M Pawlik

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