Body Mass Index Is a Marker of Nutrition Preparation Sufficiency Before Surgery for Crohn's Disease From the Perspective of Intra-Abdominal Septic Complications: A Retrospective Cohort Study

Medicine
Min ZhangHuanliang Liu

Abstract

Poor preoperative nutritional status for individuals with Crohn's disease (CD) is associated with intra-abdominal septic complications (IASCs). The present study aimed to investigate the association of the common nutrition indices serum albumin and body mass index (BMI) with IASCs. Sixty-four CD patients who had received elective intestinal operations were retrospectively investigated. Among these patients, 32 had received individualized fortified nutrition support. IASCs occurred in 7 patients (10.9%). Compared with non-IASC patients, IASC patients had a lower BMI (17.6 ± 2.7 vs 15.6 ± 1.3 kg/m, P = 0.048). The area under the receiver operating characteristic curve according to the BMI-based IASC prediction was 0.772 (95% confidence interval [CI], 0.601-0.944; P = 0.020) with an optimum diagnostic cutoff value of 16.2 kg/m. A BMI < 16.2 kg/m significantly increased the risk of developing an IASC (odds ratio [OR], 10.286; 95% CI, 1.158-91.386). Even after correction with the simplified CD activity index (CDAI), a low BMI level remained associated with IASCs (OR, 7.650; 95% CI, 0.808-72.427; P = 0.076). Serum albumin was not associated with IASCs. Although the fortified nutrition support group had an albumin level comparable to ...Continue Reading

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Citations

Sep 25, 2019·Journal of Crohn's & Colitis·Michel AdaminaMiranda Lomer
Sep 16, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·UNKNOWN 2015 European Society of Coloproctology collaborating group
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May 1, 2020·Canadian Journal of Gastroenterology & Hepatology·Christian GalataMirko Otto
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