Body mass index is associated with type 2 diabetes mellitus in Chinese elderly

Clinical Interventions in Aging
Qianping ZhaoGang Li

Abstract

There is limited information on the association between metabolic syndrome components including body mass index (BMI) and type 2 diabetes mellitus in elderly Chinese population. Therefore, we investigated whether components of metabolic syndrome are associated with type 2 diabetes mellitus in elderly. A total of 479 hospitalized patients (aged 65-95 years) with recently diagnosed type 2 diabetes mellitus were studied retrospectively in a cross-sectional study and compared with 183 subjects with prediabetes and 62 subjects without glucose metabolism abnormalities. BMI (24.69±3.59 versus 23.92±3.08 and 23.56±3.25 kg/m(2)), blood pressure, cholesterol, triglyceride, liver enzymes and prevalence of fatty liver were higher in patients with type 2 diabetes mellitus as compared with elderly subjects with prediabetes or normal glucose metabolism separately (all P<0.05). Multivariable regression analysis showed that BMI was associated positively with insulin resistance and inversely with insulin sensitivity in type 2 diabetes mellitus group (all P<0.05). Higher BMI was associated with increased insulin resistance and decreased insulin sensitivity in elderly Asian population with type 2 diabetes mellitus.

Citations

Aug 7, 2018·Journal of Magnetic Resonance Imaging : JMRI·Yuheng ChenWeiying Dai
Sep 26, 2019·Current Gene Therapy·He ZhuangShu-Lin Liu
Sep 12, 2019·Scandinavian Journal of Clinical and Laboratory Investigation·Mahroo MohamadiAli Rahimipour

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