Body-Sensor-Network-Based Kinematic Characterization and Comparative Outlook of UPDRS Scoring in Leg Agility, Sit-to-Stand, and Gait Tasks in Parkinson's Disease

IEEE Journal of Biomedical and Health Informatics
Federico ParisiAlessandro Mauro

Abstract

Recently, we have proposed a body-sensor-network-based approach, composed of a few body-worn wireless inertial nodes, for automatic assignment of Unified Parkinson's Disease Rating Scale (UPDRS) scores in the following tasks: Leg agility (LA), Sit-to-Stand (S2S), and Gait (G). Unlike our previous works and the majority of the published studies, where UPDRS tasks were the sole focus, in this paper, we carry out a comparative investigation of the LA, S2S, and G tasks. In particular, after providing an accurate description of the features identified for the kinematic characterization of the three tasks, we comment on the correlation between the most relevant kinematic parameters and the UPDRS scoring. We analyzed the performance achieved by the automatic UPDRS scoring system and compared the estimated UPDRS evaluation with the one performed by neurologists, showing that the proposed system compares favorably with typical interrater variability. We then investigated the correlations between the UPDRS scores assigned to the various tasks by both the neurologists and the automatic system. The results, based on a limited number of subjects with Parkinson's disease (PD) (34 patients, 47 clinical trials), show poor-to-moderate correlati...Continue Reading

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Citations

Dec 7, 2016·Methods of Information in Medicine·Sofija SpasojevićJosé Santos-Victor
Sep 22, 2017·Physiological Measurement·Hyoseon JeonKwang Suk Park
Jul 18, 2017·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Kramay PatelKei Masani
Oct 3, 2018·Expert Review of Neurotherapeutics·Aristide MerolaAlberto J Espay
Jan 28, 2020·Physical Therapy·Kavita VenkataramanHelen Hoenig
Feb 23, 2017·Journal of Parkinson's Disease·Hasan HasanAlastair J Noyce
Oct 9, 2019·Journal of Parkinson's Disease·Giulia Di LazzaroAntonio Pisani
Oct 24, 2017·Frontiers in Neuroscience·Erika RoviniFilippo Cavallo
Jan 29, 2021·Journal of Neural Transmission·Dong Jun ParkWeui Bong Jeong
May 7, 2021·Scientific Reports·Soroosh ShahtalebiArash Mohammadi
Oct 24, 2021·Scientific Reports·Theodoros BermperidisElizabeth B Torres

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