Body size influences energetic and osmoregulatory costs in frogs infected with Batrachochytrium dendrobatidis

Scientific Reports
Nicholas C WuCraig E Franklin

Abstract

Sloughing maintains the skins integrity and critical functionality in amphibians. Given the behavioural, morphological and osmoregulatory changes that accompany sloughing, this process is likely to be physiologically costly. Chytridiomycosis, a cutaneous disease of amphibians caused by the fungus Batrachochytrium dendrobatidis (Bd), disrupts skin function and increases sloughing rates. Moreover, mortality rates from chytridiomycosis are significantly higher in juveniles and so we hypothesised that smaller individuals maybe more susceptible to chytridiomycosis because of allometric scaling effects on the energetic and osmoregulatory costs of sloughing. We measured in-vivo cutaneous ion loss rates and whole animal metabolic rate (MR) of Green tree frogs, Litoria caerulea, over a range of body sizes both infected and uninfected frogs during sloughing. Infected animals had a greater rate of ion loss and mass-specific MR during non-sloughing periods but there were no additional effects of sloughing on either of these parameters. There were also significant interactions with body size and Bd load indicating that smaller animals with higher Bd loads have greater rates of ion loss and higher energetic demands. Our results shed light on...Continue Reading

References

Jul 1, 1989·Acta Physiologica Scandinavica·H H Ussing, K Eskesen
Jul 1, 1988·General and Comparative Endocrinology·C B Jørgensen
Nov 7, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·P E Budtz, L O Larsen
Dec 1, 1983·The American Journal of Physiology·M M CivanM Erecińska
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·L BergerH Parkes
Jan 23, 1999·Immunological Reviews·L A Rollins-Smith
Mar 29, 2001·Journal of Wildlife Diseases·D K NicholsJ E Longcore
Feb 10, 2006·Diseases of Aquatic Organisms·Lee BergerJoyce E Longcore
Sep 8, 2006·Diseases of Aquatic Organisms·Kerry M KrigerJean-Marc Hero
Nov 16, 2006·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Stephen M SecorChristian L Cox
Dec 7, 2006·Biology Letters·Craig R WhiteRoger S Seymour
Nov 2, 2007·Diseases of Aquatic Organisms·Jamie VoylesLee F Skerratt
May 16, 2008·Biometrical Journal. Biometrische Zeitschrift·Torsten HothornPeter Westfall
May 23, 2009·Science·Matthew G Vander HeidenCraig B Thompson
Jul 7, 2009·Annual Review of Microbiology·Matthew C FisherSusan F Walker
Aug 28, 2009·Proceedings. Biological Sciences·Susannah S FrenchGregory E Demas
Mar 11, 2010·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Christine E Cooper, Philip C Withers
Jul 28, 2010·Toxicon : Official Journal of the International Society on Toxinology·Anna F V PintorJamie E Seymour
Dec 21, 2011·The International Journal of Biochemistry & Cell Biology·Craig R CampbellAnuwat Dinudom
Dec 27, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·S A OrlofskeW A Hopkins
May 21, 2013·The Journal of Experimental Biology·Pieter A ArnoldCraig R White
Apr 10, 2014·Comprehensive Physiology·Erik Hviid LarsenDirk Weihrauch
Nov 27, 2015·Veterinary Research·Pascale Van RooijFrank Pasmans
Jan 29, 2016·Proceedings. Biological Sciences·C BellardJ M Jeschke
Jul 9, 2016·Developmental and Comparative Immunology·Louise A Rollins-Smith
Jun 2, 2017·The Journal of Experimental Biology·Nicholas C WuCraig E Franklin
Jun 16, 2017·Scientific Reports·Michel E B OhmerCraig E Franklin
Feb 17, 2018·Nature Communications·Kieran A BatesXavier A Harrison

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Citations

Dec 19, 2018·The Journal of Experimental Biology·Nicholas C WuCraig E Franklin
May 30, 2019·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Nicholas C WuCraig E Franklin
Apr 24, 2020·The Journal of Experimental Biology·Craig M LindTerence M Farrell
May 21, 2020·Evolutionary Applications·Maciej PabijanWiesław Babik
Jun 18, 2021·Diseases of Aquatic Organisms·Mariana Retuci PontesLuís Felipe Toledo

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